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Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism.
Cavasin MA, Demos-Davies K, Horn TR, Walker LA, Lemon DD, Birdsey N, Weiser-Evans MC, Harral J, Irwin DC, Anwar A, Yeager ME, Li M, Watson PA, Nemenoff RA, Buttrick PM, Stenmark KR, McKinsey TA. Cavasin MA, et al. Among authors: harral j. Circ Res. 2012 Mar 2;110(5):739-48. doi: 10.1161/CIRCRESAHA.111.258426. Epub 2012 Jan 26. Circ Res. 2012. PMID: 22282194 Free PMC article.
Mice deficient in galectin-1 exhibit attenuated physiological responses to chronic hypoxia-induced pulmonary hypertension.
Case D, Irwin D, Ivester C, Harral J, Morris K, Imamura M, Roedersheimer M, Patterson A, Carr M, Hagen M, Saavedra M, Crossno J Jr, Young KA, Dempsey EC, Poirier F, West J, Majka S. Case D, et al. Among authors: harral j. Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L154-64. doi: 10.1152/ajplung.00192.2006. Epub 2006 Sep 1. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 16951131 Free article.
Physiologic and molecular consequences of endothelial Bmpr2 mutation.
Majka S, Hagen M, Blackwell T, Harral J, Johnson JA, Gendron R, Paradis H, Crona D, Loyd JE, Nozik-Grayck E, Stenmark KR, West J. Majka S, et al. Among authors: harral j. Respir Res. 2011 Jun 22;12(1):84. doi: 10.1186/1465-9921-12-84. Respir Res. 2011. PMID: 21696628 Free PMC article.
Obesity-related pulmonary arterial hypertension in rats correlates with increased circulating inflammatory cytokines and lipids and with oxidant damage in the arterial wall but not with hypoxia.
Irwin DC, Garat CV, Crossno JT Jr, MacLean PS, Sullivan TM, Erickson PF, Jackman MR, Harral JW, Reusch JE, Klemm DJ. Irwin DC, et al. Among authors: harral jw. Pulm Circ. 2014 Dec;4(4):638-53. doi: 10.1086/678510. Pulm Circ. 2014. PMID: 25610600 Free PMC article.
Vascular Adaptation of the Right Ventricle in Experimental Pulmonary Hypertension.
Graham BB, Kumar R, Mickael C, Kassa B, Koyanagi D, Sanders L, Zhang L, Perez M, Hernandez-Saavedra D, Valencia C, Dixon K, Harral J, Loomis Z, Irwin D, Nemkov T, D'Alessandro A, Stenmark KR, Tuder RM. Graham BB, et al. Among authors: harral j. Am J Respir Cell Mol Biol. 2018 Oct;59(4):479-489. doi: 10.1165/rcmb.2018-0095OC. Am J Respir Cell Mol Biol. 2018. PMID: 29851508 Free PMC article.
37 results