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Sorafenib is an inhibitor of UGT1A1 but is metabolized by UGT1A9: implications of genetic variants on pharmacokinetics and hyperbilirubinemia.
Peer CJ, Sissung TM, Kim A, Jain L, Woo S, Gardner ER, Kirkland CT, Troutman SM, English BC, Richardson ED, Federspiel J, Venzon D, Dahut W, Kohn E, Kummar S, Yarchoan R, Giaccone G, Widemann B, Figg WD. Peer CJ, et al. Among authors: yarchoan r. Clin Cancer Res. 2012 Apr 1;18(7):2099-107. doi: 10.1158/1078-0432.CCR-11-2484. Epub 2012 Feb 3. Clin Cancer Res. 2012. PMID: 22307138 Free PMC article.
Phase II trial with dose titration of paclitaxel for the therapy of human immunodeficiency virus-associated Kaposi's sarcoma.
Welles L, Saville MW, Lietzau J, Pluda JM, Wyvill KM, Feuerstein I, Figg WD, Lush R, Odom J, Wilson WH, Fajardo MT, Humphrey RW, Feigal E, Tuck D, Steinberg SM, Broder S, Yarchoan R. Welles L, et al. Among authors: yarchoan r. J Clin Oncol. 1998 Mar;16(3):1112-21. doi: 10.1200/JCO.1998.16.3.1112. J Clin Oncol. 1998. PMID: 9508198 Clinical Trial.
Activity of thalidomide in AIDS-related Kaposi's sarcoma.
Little RF, Wyvill KM, Pluda JM, Welles L, Marshall V, Figg WD, Newcomb FM, Tosato G, Feigal E, Steinberg SM, Whitby D, Goedert JJ, Yarchoan R. Little RF, et al. Among authors: yarchoan r. J Clin Oncol. 2000 Jul;18(13):2593-602. doi: 10.1200/JCO.2000.18.13.2593. J Clin Oncol. 2000. PMID: 10893291 Clinical Trial.
328 results