Tainer JA - Search Results

1

Flap endonucleases pass 5'-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5'-ends.

Patel N, Atack JM, Finger LD, Exell JC, Thompson P, Tsutakawa S, Tainer JA, Williams DM, Grasby JA. Patel N, et al. Among authors: tainer ja. Nucleic Acids Res. 2012 May;40(10):4507-19. doi: 10.1093/nar/gks051. Epub 2012 Feb 8. Nucleic Acids Res. 2012. PMID: 22319208 Free PMC article.

2

Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome.

Sarker AH, Tsutakawa SE, Kostek S, Ng C, Shin DS, Peris M, Campeau E, Tainer JA, Nogales E, Cooper PK. Sarker AH, et al. Among authors: tainer ja. Mol Cell. 2005 Oct 28;20(2):187-98. doi: 10.1016/j.molcel.2005.09.022. Mol Cell. 2005. PMID: 16246722 Free article.

3

Proliferating cell nuclear antigen loaded onto double-stranded DNA: dynamics, minor groove interactions and functional implications.

Ivanov I, Chapados BR, McCammon JA, Tainer JA. Ivanov I, et al. Among authors: tainer ja. Nucleic Acids Res. 2006;34(20):6023-33. doi: 10.1093/nar/gkl744. Epub 2006 Oct 27. Nucleic Acids Res. 2006. PMID: 17071716 Free PMC article.

4

Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography.

Tsutakawa SE, Hura GL, Frankel KA, Cooper PK, Tainer JA. Tsutakawa SE, et al. Among authors: tainer ja. J Struct Biol. 2007 May;158(2):214-23. doi: 10.1016/j.jsb.2006.09.008. Epub 2006 Oct 27. J Struct Biol. 2007. PMID: 17182256

5

Comparison of the catalytic parameters and reaction specificities of a phage and an archaeal flap endonuclease.

Williams R, Sengerová B, Osborne S, Syson K, Ault S, Kilgour A, Chapados BR, Tainer JA, Sayers JR, Grasby JA. Williams R, et al. Among authors: tainer ja. J Mol Biol. 2007 Aug 3;371(1):34-48. doi: 10.1016/j.jmb.2007.04.063. Epub 2007 May 1. J Mol Biol. 2007. PMID: 17559871 Free PMC article.

6

Three metal ions participate in the reaction catalyzed by T5 flap endonuclease.

Syson K, Tomlinson C, Chapados BR, Sayers JR, Tainer JA, Williams NH, Grasby JA. Syson K, et al. Among authors: tainer ja. J Biol Chem. 2008 Oct 17;283(42):28741-6. doi: 10.1074/jbc.M801264200. Epub 2008 Aug 11. J Biol Chem. 2008. PMID: 18697748 Free PMC article.

7

The structure of the MAP2K MEK6 reveals an autoinhibitory dimer.

Min X, Akella R, He H, Humphreys JM, Tsutakawa SE, Lee SJ, Tainer JA, Cobb MH, Goldsmith EJ. Min X, et al. Among authors: tainer ja. Structure. 2009 Jan 14;17(1):96-104. doi: 10.1016/j.str.2008.11.007. Structure. 2009. PMID: 19141286 Free PMC article.

8

Flipping of alkylated DNA damage bridges base and nucleotide excision repair.

Tubbs JL, Latypov V, Kanugula S, Butt A, Melikishvili M, Kraehenbuehl R, Fleck O, Marriott A, Watson AJ, Verbeek B, McGown G, Thorncroft M, Santibanez-Koref MF, Millington C, Arvai AS, Kroeger MD, Peterson LA, Williams DM, Fried MG, Margison GP, Pegg AE, Tainer JA. Tubbs JL, et al. Among authors: tainer ja. Nature. 2009 Jun 11;459(7248):808-13. doi: 10.1038/nature08076. Nature. 2009. PMID: 19516334 Free PMC article.

9

Structural dynamics and single-stranded DNA binding activity of the three N-terminal domains of the large subunit of replication protein A from small angle X-ray scattering.

Pretto DI, Tsutakawa S, Brosey CA, Castillo A, Chagot ME, Smith JA, Tainer JA, Chazin WJ. Pretto DI, et al. Among authors: tainer ja. Biochemistry. 2010 Apr 6;49(13):2880-9. doi: 10.1021/bi9019934. Biochemistry. 2010. PMID: 20184389 Free PMC article.

10

Substrate recognition and catalysis by flap endonucleases and related enzymes.

Tomlinson CG, Atack JM, Chapados B, Tainer JA, Grasby JA. Tomlinson CG, et al. Among authors: tainer ja. Biochem Soc Trans. 2010 Apr;38(2):433-7. doi: 10.1042/BST0380433. Biochem Soc Trans. 2010. PMID: 20298197 Review.

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