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Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics.
Abo R, Hebbring S, Ji Y, Zhu H, Zeng ZB, Batzler A, Jenkins GD, Biernacka J, Snyder K, Drews M, Fiehn O, Fridley B, Schaid D, Kamatani N, Nakamura Y, Kubo M, Mushiroda T, Kaddurah-Daouk R, Mrazek DA, Weinshilboum RM. Abo R, et al. Among authors: zhu h. Pharmacogenet Genomics. 2012 Apr;22(4):247-53. doi: 10.1097/FPC.0b013e32835001c9. Pharmacogenet Genomics. 2012. PMID: 22322242 Free PMC article.
TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics.
Gupta M, Neavin D, Liu D, Biernacka J, Hall-Flavin D, Bobo WV, Frye MA, Skime M, Jenkins GD, Batzler A, Kalari K, Matson W, Bhasin SS, Zhu H, Mushiroda T, Nakamura Y, Kubo M, Wang L, Kaddurah-Daouk R, Weinshilboum RM. Gupta M, et al. Among authors: zhu h. Mol Psychiatry. 2016 Dec;21(12):1717-1725. doi: 10.1038/mp.2016.6. Epub 2016 Feb 23. Mol Psychiatry. 2016. PMID: 26903268 Free PMC article.
Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics.
Ji Y, Hebbring S, Zhu H, Jenkins GD, Biernacka J, Snyder K, Drews M, Fiehn O, Zeng Z, Schaid D, Mrazek DA, Kaddurah-Daouk R, Weinshilboum RM. Ji Y, et al. Among authors: zhu h. Clin Pharmacol Ther. 2011 Jan;89(1):97-104. doi: 10.1038/clpt.2010.250. Epub 2010 Nov 24. Clin Pharmacol Ther. 2011. PMID: 21107318 Free PMC article. Clinical Trial.
Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.
Liu D, Ray B, Neavin DR, Zhang J, Athreya AP, Biernacka JM, Bobo WV, Hall-Flavin DK, Skime MK, Zhu H, Jenkins GD, Batzler A, Kalari KR, Boakye-Agyeman F, Matson WR, Bhasin SS, Mushiroda T, Nakamura Y, Kubo M, Iyer RK, Wang L, Frye MA, Kaddurah-Daouk R, Weinshilboum RM. Liu D, et al. Among authors: zhu h. Transl Psychiatry. 2018 Jan 10;8(1):10. doi: 10.1038/s41398-017-0056-8. Transl Psychiatry. 2018. PMID: 29317604 Free PMC article.
Metabolomic signature of exposure and response to citalopram/escitalopram in depressed outpatients.
Bhattacharyya S, Ahmed AT, Arnold M, Liu D, Luo C, Zhu H, Mahmoudiandehkordi S, Neavin D, Louie G, Dunlop BW, Frye MA, Wang L, Weinshilboum RM, Krishnan RR, Rush AJ, Kaddurah-Daouk R. Bhattacharyya S, et al. Among authors: zhu h. Transl Psychiatry. 2019 Jul 4;9(1):173. doi: 10.1038/s41398-019-0507-5. Transl Psychiatry. 2019. PMID: 31273200 Free PMC article. Clinical Trial.
Pharmacometabolomics reveals racial differences in response to atenolol treatment.
Wikoff WR, Frye RF, Zhu H, Gong Y, Boyle S, Churchill E, Cooper-Dehoff RM, Beitelshees AL, Chapman AB, Fiehn O, Johnson JA, Kaddurah-Daouk R; Pharmacometabolomics Research Network. Wikoff WR, et al. Among authors: zhu h. PLoS One. 2013;8(3):e57639. doi: 10.1371/journal.pone.0057639. Epub 2013 Mar 11. PLoS One. 2013. PMID: 23536766 Free PMC article.
Pharmacometabolomics of response to sertraline and to placebo in major depressive disorder - possible role for methoxyindole pathway.
Zhu H, Bogdanov MB, Boyle SH, Matson W, Sharma S, Matson S, Churchill E, Fiehn O, Rush JA, Krishnan RR, Pickering E, Delnomdedieu M, Kaddurah-Daouk R; Pharmacometabolomics Research Network. Zhu H, et al. PLoS One. 2013 Jul 17;8(7):e68283. doi: 10.1371/journal.pone.0068283. Print 2013. PLoS One. 2013. PMID: 23874572 Free PMC article. Clinical Trial.
Pharmacometabolomics of statin response.
Krauss RM, Zhu H, Kaddurah-Daouk R. Krauss RM, et al. Among authors: zhu h. Clin Pharmacol Ther. 2013 Nov;94(5):562-5. doi: 10.1038/clpt.2013.164. Epub 2013 Aug 14. Clin Pharmacol Ther. 2013. PMID: 23945822 Free PMC article. Review.
Enteric microbiome metabolites correlate with response to simvastatin treatment.
Kaddurah-Daouk R, Baillie RA, Zhu H, Zeng ZB, Wiest MM, Nguyen UT, Wojnoonski K, Watkins SM, Trupp M, Krauss RM. Kaddurah-Daouk R, et al. Among authors: zhu h. PLoS One. 2011;6(10):e25482. doi: 10.1371/journal.pone.0025482. Epub 2011 Oct 13. PLoS One. 2011. PMID: 22022402 Free PMC article.
Purine pathway implicated in mechanism of resistance to aspirin therapy: pharmacometabolomics-informed pharmacogenomics.
Yerges-Armstrong LM, Ellero-Simatos S, Georgiades A, Zhu H, Lewis JP, Horenstein RB, Beitelshees AL, Dane A, Reijmers T, Hankemeier T, Fiehn O, Shuldiner AR, Kaddurah-Daouk R. Yerges-Armstrong LM, et al. Among authors: zhu h. Clin Pharmacol Ther. 2013 Oct;94(4):525-32. doi: 10.1038/clpt.2013.119. Epub 2013 Jun 11. Clin Pharmacol Ther. 2013. PMID: 23839601 Free PMC article. Clinical Trial.
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