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Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased β-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort.
Harder MN, Ribel-Madsen R, Justesen JM, Sparsø T, Andersson EA, Grarup N, Jørgensen T, Linneberg A, Hansen T, Pedersen O. Harder MN, et al. J Clin Endocrinol Metab. 2013 Apr;98(4):E801-6. doi: 10.1210/jc.2012-4169. Epub 2013 Mar 1. J Clin Endocrinol Metab. 2013. PMID: 23457408
Genetic risk score of 46 type 2 diabetes risk variants associates with changes in plasma glucose and estimates of pancreatic β-cell function over 5 years of follow-up.
Andersson EA, Allin KH, Sandholt CH, Borglykke A, Lau CJ, Ribel-Madsen R, Sparsø T, Justesen JM, Harder MN, Jørgensen ME, Jørgensen T, Hansen T, Pedersen O. Andersson EA, et al. Diabetes. 2013 Oct;62(10):3610-7. doi: 10.2337/db13-0362. Epub 2013 Jul 8. Diabetes. 2013. PMID: 23835328 Free PMC article. Clinical Trial.
Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population.
Vestmar MA, Andersson EA, Christensen CR, Hauge M, Glümer C, Linneberg A, Witte DR, Jørgensen ME, Christensen C, Brandslund I, Lauritzen T, Pedersen O, Holst B, Grarup N, Schwartz TW, Hansen T. Vestmar MA, et al. Among authors: andersson ea. J Med Genet. 2016 Sep;53(9):616-23. doi: 10.1136/jmedgenet-2015-103728. Epub 2016 Apr 11. J Med Genet. 2016. PMID: 27068006
The birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associates with elevated insulin release following an oral glucose challenge.
Andersson EA, Harder MN, Pilgaard K, Pisinger C, Stančáková A, Kuusisto J, Grarup N, Færch K, Poulsen P, Witte DR, Jørgensen T, Vaag A, Laakso M, Pedersen O, Hansen T. Andersson EA, et al. PLoS One. 2011;6(11):e27096. doi: 10.1371/journal.pone.0027096. Epub 2011 Nov 4. PLoS One. 2011. PMID: 22073261 Free PMC article.
A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals.
Krarup NT, Borglykke A, Allin KH, Sandholt CH, Justesen JM, Andersson EA, Grarup N, Jørgensen T, Pedersen O, Hansen T. Krarup NT, et al. Among authors: andersson ea. Atherosclerosis. 2015 Jun;240(2):305-10. doi: 10.1016/j.atherosclerosis.2015.03.022. Epub 2015 Mar 16. Atherosclerosis. 2015. PMID: 25864160 Clinical Trial.
G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.
Sparsø T, Bonnefond A, Andersson E, Bouatia-Naji N, Holmkvist J, Wegner L, Grarup N, Gjesing AP, Banasik K, Cavalcanti-Proença C, Marchand M, Vaxillaire M, Charpentier G, Jarvelin MR, Tichet J, Balkau B, Marre M, Lévy-Marchal C, Faerch K, Borch-Johnsen K, Jørgensen T, Madsbad S, Poulsen P, Vaag A, Dina C, Hansen T, Pedersen O, Froguel P. Sparsø T, et al. Among authors: andersson e. Diabetes. 2009 Jun;58(6):1450-6. doi: 10.2337/db08-1660. Epub 2009 Mar 26. Diabetes. 2009. PMID: 19324940 Free PMC article.
1,183 results