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The Smac mimetic RMT5265.2HCL induces apoptosis in EBV and HTLV-I associated lymphoma cells by inhibiting XIAP and promoting the mitochondrial release of cytochrome C and Smac.
Ramachandiran S, Cain J, Liao A, He Y, Guo X, Boise LH, Fu H, Ratner L, Khoury HJ, Bernal-Mizrachi L. Ramachandiran S, et al. Among authors: fu h. Leuk Res. 2012 Jun;36(6):784-90. doi: 10.1016/j.leukres.2011.12.024. Epub 2012 Feb 10. Leuk Res. 2012. PMID: 22325366 Free PMC article.
Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κB pathway.
Ramachandiran S, Adon A, Guo X, Wang Y, Wang H, Chen Z, Kowalski J, Sunay UR, Young AN, Brown T, Mar JC, Du Y, Fu H, Mann KP, Natkunam Y, Boise LH, Saavedra HI, Lossos IS, Bernal-Mizrachi L. Ramachandiran S, et al. Among authors: fu h. Int J Cancer. 2015 May 15;136(10):2341-51. doi: 10.1002/ijc.29301. Epub 2014 Nov 11. Int J Cancer. 2015. PMID: 25359525 Free PMC article.
7,725 results