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The Smac mimetic RMT5265.2HCL induces apoptosis in EBV and HTLV-I associated lymphoma cells by inhibiting XIAP and promoting the mitochondrial release of cytochrome C and Smac.
Ramachandiran S, Cain J, Liao A, He Y, Guo X, Boise LH, Fu H, Ratner L, Khoury HJ, Bernal-Mizrachi L. Ramachandiran S, et al. Among authors: ratner l. Leuk Res. 2012 Jun;36(6):784-90. doi: 10.1016/j.leukres.2011.12.024. Epub 2012 Feb 10. Leuk Res. 2012. PMID: 22325366 Free PMC article.
Outcome of patients with relapsed/refractory acquired immune deficiency syndrome-related lymphoma diagnosed 1999-2008 and treated with curative intent in the AIDS Malignancy Consortium.
Bayraktar UD, Ramos JC, Petrich A, Gupta N, Lensing S, Moore PC, Reid EG, Aboulafia DM, Ratner L, Mitsuyasu R, Cooley T, Henry DH, Barr P, Noy A. Bayraktar UD, et al. Among authors: ratner l. Leuk Lymphoma. 2012 Dec;53(12):2383-9. doi: 10.3109/10428194.2012.697559. Epub 2012 Jul 9. Leuk Lymphoma. 2012. PMID: 22642936 Free PMC article.
How does HTLV-1 cause adult T-cell leukaemia/lymphoma (ATL)?
Bangham CR, Ratner L. Bangham CR, et al. Among authors: ratner l. Curr Opin Virol. 2015 Oct;14:93-100. doi: 10.1016/j.coviro.2015.09.004. Epub 2015 Sep 27. Curr Opin Virol. 2015. PMID: 26414684 Free PMC article. Review.
Safety and Preliminary Efficacy of Vorinostat With R-EPOCH in High-risk HIV-associated Non-Hodgkin's Lymphoma (AMC-075).
Ramos JC, Sparano JA, Rudek MA, Moore PC, Cesarman E, Reid EG, Henry D, Ratner L, Aboulafia D, Lee JY, Ambinder RF, Mitsuyasu R, Noy A. Ramos JC, et al. Among authors: ratner l. Clin Lymphoma Myeloma Leuk. 2018 Mar;18(3):180-190.e2. doi: 10.1016/j.clml.2018.01.004. Epub 2018 Feb 2. Clin Lymphoma Myeloma Leuk. 2018. PMID: 29426719 Free PMC article. Clinical Trial.
IRF-4 and c-Rel expression in antiviral-resistant adult T-cell leukemia/lymphoma.
Ramos JC, Ruiz P Jr, Ratner L, Reis IM, Brites C, Pedroso C, Byrne GE Jr, Toomey NL, Andela V, Harhaj EW, Lossos IS, Harrington WJ Jr. Ramos JC, et al. Among authors: ratner l. Blood. 2007 Apr 1;109(7):3060-8. doi: 10.1182/blood-2006-07-036368. Blood. 2007. PMID: 17138822 Free PMC article.
628 results