Bromberg J - Search Results

1

Targeting the interleukin-6/Jak/stat pathway in human malignancies.

Sansone P, Bromberg J. Sansone P, et al. Among authors: bromberg j. J Clin Oncol. 2012 Mar 20;30(9):1005-14. doi: 10.1200/JCO.2010.31.8907. Epub 2012 Feb 21. J Clin Oncol. 2012. PMID: 22355058 Free PMC article. Review.

2

Pyridone 6, a pan-Janus-activated kinase inhibitor, induces growth inhibition of multiple myeloma cells.

Pedranzini L, Dechow T, Berishaj M, Comenzo R, Zhou P, Azare J, Bornmann W, Bromberg J. Pedranzini L, et al. Among authors: bromberg j. Cancer Res. 2006 Oct 1;66(19):9714-21. doi: 10.1158/0008-5472.CAN-05-4280. Cancer Res. 2006. PMID: 17018630

3

Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer.

Berishaj M, Gao SP, Ahmed S, Leslie K, Al-Ahmadie H, Gerald WL, Bornmann W, Bromberg JF. Berishaj M, et al. Breast Cancer Res. 2007;9(3):R32. doi: 10.1186/bcr1680. Breast Cancer Res. 2007. PMID: 17531096 Free PMC article.

4

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas.

Gao SP, Mark KG, Leslie K, Pao W, Motoi N, Gerald WL, Travis WD, Bornmann W, Veach D, Clarkson B, Bromberg JF. Gao SP, et al. J Clin Invest. 2007 Dec;117(12):3846-56. doi: 10.1172/JCI31871. J Clin Invest. 2007. PMID: 18060032 Free PMC article.

5

Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness.

de la Iglesia N, Konopka G, Lim KL, Nutt CL, Bromberg JF, Frank DA, Mischel PS, Louis DN, Bonni A. de la Iglesia N, et al. J Neurosci. 2008 Jun 4;28(23):5870-8. doi: 10.1523/JNEUROSCI.5385-07.2008. J Neurosci. 2008. PMID: 18524891 Free PMC article.

6

Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis.

Koppikar P, Abdel-Wahab O, Hedvat C, Marubayashi S, Patel J, Goel A, Kucine N, Gardner JR, Combs AP, Vaddi K, Haley PJ, Burn TC, Rupar M, Bromberg JF, Heaney ML, de Stanchina E, Fridman JS, Levine RL. Koppikar P, et al. Among authors: bromberg jf. Blood. 2010 Apr 8;115(14):2919-27. doi: 10.1182/blood-2009-04-218842. Epub 2010 Feb 12. Blood. 2010. PMID: 20154217 Free PMC article.

7

Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation.

Leslie K, Gao SP, Berishaj M, Podsypanina K, Ho H, Ivashkiv L, Bromberg J. Leslie K, et al. Among authors: bromberg j. Breast Cancer Res. 2010;12(5):R80. doi: 10.1186/bcr2725. Epub 2010 Oct 7. Breast Cancer Res. 2010. PMID: 20929542 Free PMC article.

8

Environment, inflammation, and cancer.

Sansone P, Bromberg J. Sansone P, et al. Among authors: bromberg j. Curr Opin Genet Dev. 2011 Feb;21(1):80-5. doi: 10.1016/j.gde.2010.11.001. Epub 2010 Dec 6. Curr Opin Genet Dev. 2011. PMID: 21144738 Review.

9

The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis.

Chang Q, Bournazou E, Sansone P, Berishaj M, Gao SP, Daly L, Wels J, Theilen T, Granitto S, Zhang X, Cotari J, Alpaugh ML, de Stanchina E, Manova K, Li M, Bonafe M, Ceccarelli C, Taffurelli M, Santini D, Altan-Bonnet G, Kaplan R, Norton L, Nishimoto N, Huszar D, Lyden D, Bromberg J. Chang Q, et al. Among authors: bromberg j. Neoplasia. 2013 Jul;15(7):848-62. doi: 10.1593/neo.13706. Neoplasia. 2013. PMID: 23814496 Free PMC article.

10

Targeting the tumor microenvironment: JAK-STAT3 signaling.

Bournazou E, Bromberg J. Bournazou E, et al. Among authors: bromberg j. JAKSTAT. 2013 Apr 1;2(2):e23828. doi: 10.4161/jkst.23828. JAKSTAT. 2013. PMID: 24058812 Free PMC article. Review.

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