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Inhibition of FOXC2 restores epithelial phenotype and drug sensitivity in prostate cancer cells with stem-cell properties.
Paranjape AN, Soundararajan R, Werden SJ, Joseph R, Taube JH, Liu H, Rodriguez-Canales J, Sphyris N, Wistuba I, Miura N, Dhillon J, Mahajan N, Mahajan K, Chang JT, Ittmann M, Maity SN, Logothetis C, Tang DG, Mani SA. Paranjape AN, et al. Among authors: dhillon j. Oncogene. 2016 Nov 17;35(46):5963-5976. doi: 10.1038/onc.2015.498. Epub 2016 Jan 25. Oncogene. 2016. PMID: 26804168 Free PMC article.
Targeting the BRD4-HOXB13 Coregulated Transcriptional Networks with Bromodomain-Kinase Inhibitors to Suppress Metastatic Castration-Resistant Prostate Cancer.
Nerlakanti N, Yao J, Nguyen DT, Patel AK, Eroshkin AM, Lawrence HR, Ayaz M, Kuenzi BM, Agarwal N, Chen Y, Gunawan S, Karim RM, Berndt N, Puskas J, Magliocco AM, Coppola D, Dhillon J, Zhang J, Shymalagovindarajan S, Rix U, Kim Y, Perera R, Lawrence NJ, Schonbrunn E, Mahajan K. Nerlakanti N, et al. Among authors: dhillon j. Mol Cancer Ther. 2018 Dec;17(12):2796-2810. doi: 10.1158/1535-7163.MCT-18-0602. Epub 2018 Sep 21. Mol Cancer Ther. 2018. PMID: 30242092 Free PMC article.
Tumor-derived OBP2A promotes prostate cancer castration resistance.
Jeong JH, Zhong S, Li F, Huang C, Chen X, Liu Q, Peng S, Park H, Lee YM, Dhillon J, Luo JL. Jeong JH, et al. Among authors: dhillon j. J Exp Med. 2023 Mar 6;220(3):e20211546. doi: 10.1084/jem.20211546. Epub 2022 Dec 22. J Exp Med. 2023. PMID: 36547668 Free PMC article.
Distinct transcriptional repertoire of the androgen receptor in ETS fusion-negative prostate cancer.
Berglund AE, Rounbehler RJ, Gerke T, Awasthi S, Cheng CH, Takhar M, Davicioni E, Alshalalfa M, Erho N, Klein EA, Freedland SJ, Ross AE, Schaeffer EM, Trock BJ, Den RB, Cleveland JL, Park JY, Dhillon J, Yamoah K. Berglund AE, et al. Among authors: dhillon j. Prostate Cancer Prostatic Dis. 2019 May;22(2):292-302. doi: 10.1038/s41391-018-0103-4. Epub 2018 Oct 26. Prostate Cancer Prostatic Dis. 2019. PMID: 30367117 Free PMC article.
Macrophage-Derived Cholesterol Contributes to Therapeutic Resistance in Prostate Cancer.
El-Kenawi A, Dominguez-Viqueira W, Liu M, Awasthi S, Abraham-Miranda J, Keske A, Steiner KK, Noel L, Serna AN, Dhillon J, Gillies RJ, Yu X, Koomen JM, Yamoah K, Gatenby RA, Ruffell B. El-Kenawi A, et al. Among authors: dhillon j. Cancer Res. 2021 Nov 1;81(21):5477-5490. doi: 10.1158/0008-5472.CAN-20-4028. Epub 2021 Jul 23. Cancer Res. 2021. PMID: 34301759 Free PMC article.
Proof-of-principle Phase I results of combining nivolumab with brachytherapy and external beam radiation therapy for Grade Group 5 prostate cancer: safety, feasibility, and exploratory analysis.
Yuan Z, Fernandez D, Dhillon J, Abraham-Miranda J, Awasthi S, Kim Y, Zhang J, Jain R, Serna A, Pow-Sang JM, Poch M, Li R, Manley B, Fink A, Naghavi A, Torres-Roca JF, Grass GD, Kim S, Latifi K, Hunt D, Johnstone PAS, Yamoah K. Yuan Z, et al. Among authors: dhillon j. Prostate Cancer Prostatic Dis. 2021 Mar;24(1):140-149. doi: 10.1038/s41391-020-0254-y. Epub 2020 Jul 10. Prostate Cancer Prostatic Dis. 2021. PMID: 32651467 Free PMC article. Clinical Trial.
Spatial clustering of CD68+ tumor associated macrophages with tumor cells is associated with worse overall survival in metastatic clear cell renal cell carcinoma.
Chakiryan NH, Kimmel GJ, Kim Y, Hajiran A, Aydin AM, Zemp L, Katende E, Nguyen J, Lopez-Blanco N, Chahoud J, Spiess PE, Fournier M, Dhillon J, Wang L, Moran-Segura C, El-Kenawi A, Mulé J, Altrock PM, Manley BJ. Chakiryan NH, et al. Among authors: dhillon j. PLoS One. 2021 Apr 21;16(4):e0245415. doi: 10.1371/journal.pone.0245415. eCollection 2021. PLoS One. 2021. PMID: 33882057 Free PMC article.
298 results