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Genetic deficiency in plasma protein HRG enhances tumor growth and metastasis by exacerbating immune escape and vessel abnormalization.
Tugues S, Honjo S, König C, Noguer O, Hedlund M, Botling J, Deschoemaeker S, Wenes M, Rolny C, Jahnen-Dechent W, Mazzone M, Claesson-Welsh L. Tugues S, et al. Among authors: konig c. Cancer Res. 2012 Apr 15;72(8):1953-63. doi: 10.1158/0008-5472.CAN-11-2194. Epub 2012 Feb 28. Cancer Res. 2012. PMID: 22374984 Free article.
Tetraspanin CD63 promotes vascular endothelial growth factor receptor 2-β1 integrin complex formation, thereby regulating activation and downstream signaling in endothelial cells in vitro and in vivo.
Tugues S, Honjo S, König C, Padhan N, Kroon J, Gualandi L, Li X, Barkefors I, Thijssen VL, Griffioen AW, Claesson-Welsh L. Tugues S, et al. Among authors: konig c. J Biol Chem. 2013 Jun 28;288(26):19060-71. doi: 10.1074/jbc.M113.468199. Epub 2013 Apr 30. J Biol Chem. 2013. PMID: 23632027 Free PMC article.
Targeting PI3K in neuroblastoma.
Spitzenberg V, König C, Ulm S, Marone R, Röpke L, Müller JP, Grün M, Bauer R, Rubio I, Wymann MP, Voigt A, Wetzker R. Spitzenberg V, et al. Among authors: konig c. J Cancer Res Clin Oncol. 2010 Dec;136(12):1881-90. doi: 10.1007/s00432-010-0847-2. Epub 2010 Mar 12. J Cancer Res Clin Oncol. 2010. PMID: 20224967
PI3Kγ integrates cAMP and Akt signalling of the μ-opioid receptor.
Madishetti S, Schneble N, König C, Hirsch E, Schulz S, Müller JP, Wetzker R. Madishetti S, et al. Among authors: konig c. Br J Pharmacol. 2014 Jul;171(13):3328-37. doi: 10.1111/bph.12698. Br J Pharmacol. 2014. PMID: 24654606 Free PMC article.
452 results