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Bioinformatics and systems biology.
Ram PT, Mendelsohn J, Mills GB. Ram PT, et al. Mol Oncol. 2012 Apr;6(2):147-54. doi: 10.1016/j.molonc.2012.01.008. Epub 2012 Feb 17. Mol Oncol. 2012. PMID: 22377422 Free PMC article. Review.
Cancer Systems Biology: a peek into the future of patient care?
Werner HM, Mills GB, Ram PT. Werner HM, et al. Among authors: ram pt. Nat Rev Clin Oncol. 2014 Mar;11(3):167-76. doi: 10.1038/nrclinonc.2014.6. Epub 2014 Feb 4. Nat Rev Clin Oncol. 2014. PMID: 24492837 Free PMC article. Review.
Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks.
Chiu HS, Llobet-Navas D, Yang X, Chung WJ, Ambesi-Impiombato A, Iyer A, Kim HR, Seviour EG, Luo Z, Sehgal V, Moss T, Lu Y, Ram P, Silva J, Mills GB, Califano A, Sumazin P. Chiu HS, et al. Genome Res. 2015 Feb;25(2):257-67. doi: 10.1101/gr.178194.114. Epub 2014 Nov 5. Genome Res. 2015. PMID: 25378249 Free PMC article.
Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers.
Chaluvally-Raghavan P, Zhang F, Pradeep S, Hamilton MP, Zhao X, Rupaimoole R, Moss T, Lu Y, Yu S, Pecot CV, Aure MR, Peuget S, Rodriguez-Aguayo C, Han HD, Zhang D, Venkatanarayan A, Krohn M, Kristensen VN, Gagea M, Ram P, Liu W, Lopez-Berestein G, Lorenzi PL, Børresen-Dale AL, Chin K, Gray J, Dusetti NJ, McGuire SE, Flores ER, Sood AK, Mills GB. Chaluvally-Raghavan P, et al. Cancer Cell. 2014 Dec 8;26(6):863-879. doi: 10.1016/j.ccell.2014.10.010. Cancer Cell. 2014. PMID: 25490449 Free PMC article.
Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanoma.
Gopal YN, Rizos H, Chen G, Deng W, Frederick DT, Cooper ZA, Scolyer RA, Pupo G, Komurov K, Sehgal V, Zhang J, Patel L, Pereira CG, Broom BM, Mills GB, Ram P, Smith PD, Wargo JA, Long GV, Davies MA. Gopal YN, et al. Cancer Res. 2014 Dec 1;74(23):7037-47. doi: 10.1158/0008-5472.CAN-14-1392. Epub 2014 Oct 8. Cancer Res. 2014. PMID: 25297634 Free PMC article.
A pan-cancer proteomic perspective on The Cancer Genome Atlas.
Akbani R, Ng PK, Werner HM, Shahmoradgoli M, Zhang F, Ju Z, Liu W, Yang JY, Yoshihara K, Li J, Ling S, Seviour EG, Ram PT, Minna JD, Diao L, Tong P, Heymach JV, Hill SM, Dondelinger F, Städler N, Byers LA, Meric-Bernstam F, Weinstein JN, Broom BM, Verhaak RG, Liang H, Mukherjee S, Lu Y, Mills GB. Akbani R, et al. Among authors: ram pt. Nat Commun. 2014 May 29;5:3887. doi: 10.1038/ncomms4887. Nat Commun. 2014. PMID: 24871328 Free PMC article.
Genome-wide perturbations by miRNAs map onto functional cellular pathways, identifying regulators of chromatin modifiers.
Moss TJ, Luo Z, Seviour EG, Sehgal V, Lu Y, Hill SM, Rupaimoole R, Lee JS, Rodriguez-Aguayo C, Lopez-Berestein G, Sood AK, Azencott R, Gray JW, Mukherjee S, Mills GB, Ram PT. Moss TJ, et al. Among authors: ram pt. NPJ Syst Biol Appl. 2015 Sep 28;1:15001. doi: 10.1038/npjsba.2015.1. eCollection 2015. NPJ Syst Biol Appl. 2015. PMID: 28725457 Free PMC article.
88 results