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Genome-wide association analysis of ischemic stroke in young adults.
Cheng YC, O'Connell JR, Cole JW, Stine OC, Dueker N, McArdle PF, Sparks MJ, Shen J, Laurie CC, Nelson S, Doheny KF, Ling H, Pugh EW, Brott TG, Brown RD Jr, Meschia JF, Nalls M, Rich SS, Worrall B, Anderson CD, Biffi A, Cortellini L, Furie KL, Rost NS, Rosand J, Manolio TA, Kittner SJ, Mitchell BD. Cheng YC, et al. Among authors: mcardle pf. G3 (Bethesda). 2011 Nov;1(6):505-14. doi: 10.1534/g3.111.001164. Epub 2011 Nov 1. G3 (Bethesda). 2011. PMID: 22384361 Free PMC article.
Obesity increases risk of ischemic stroke in young adults.
Mitchell AB, Cole JW, McArdle PF, Cheng YC, Ryan KA, Sparks MJ, Mitchell BD, Kittner SJ. Mitchell AB, et al. Among authors: mcardle pf. Stroke. 2015 Jun;46(6):1690-2. doi: 10.1161/STROKEAHA.115.008940. Epub 2015 May 5. Stroke. 2015. PMID: 25944320 Free PMC article. Clinical Trial.
Stroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes.
Meschia JF, Arnett DK, Ay H, Brown RD Jr, Benavente OR, Cole JW, de Bakker PI, Dichgans M, Doheny KF, Fornage M, Grewal RP, Gwinn K, Jern C, Conde JJ, Johnson JA, Jood K, Laurie CC, Lee JM, Lindgren A, Markus HS, McArdle PF, McClure LA, Mitchell BD, Schmidt R, Rexrode KM, Rich SS, Rosand J, Rothwell PM, Rundek T, Sacco RL, Sharma P, Shuldiner AR, Slowik A, Wassertheil-Smoller S, Sudlow C, Thijs VN, Woo D, Worrall BB, Wu O, Kittner SJ; NINDS SiGN Study. Meschia JF, et al. Among authors: mcardle pf. Stroke. 2013 Oct;44(10):2694-702. doi: 10.1161/STROKEAHA.113.001857. Epub 2013 Sep 10. Stroke. 2013. PMID: 24021684 Free PMC article.
Prothrombin G20210A mutation is associated with young-onset stroke: the genetics of early-onset stroke study and meta-analysis.
Jiang B, Ryan KA, Hamedani A, Cheng Y, Sparks MJ, Koontz D, Bean CJ, Gallagher M, Hooper WC, McArdle PF, O'Connell JR, Stine OC, Wozniak MA, Stern BJ, Mitchell BD, Kittner SJ, Cole JW. Jiang B, et al. Among authors: mcardle pf. Stroke. 2014 Apr;45(4):961-7. doi: 10.1161/STROKEAHA.113.004063. Epub 2014 Mar 11. Stroke. 2014. PMID: 24619398 Free PMC article.
Using previously genotyped controls in genome-wide association studies (GWAS): application to the Stroke Genetics Network (SiGN).
Mitchell BD, Fornage M, McArdle PF, Cheng YC, Pulit SL, Wong Q, Dave T, Williams SR, Corriveau R, Gwinn K, Doheny K, Laurie CC, Rich SS, de Bakker PI; Stroke Genetics Network (SiGN). Mitchell BD, et al. Among authors: mcardle pf. Front Genet. 2014 Apr 29;5:95. doi: 10.3389/fgene.2014.00095. eCollection 2014. Front Genet. 2014. PMID: 24808905 Free PMC article.
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD Jr, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K, Reiner AP, Rexrode KM, Rice K, Rich SS, Ridker PM, Rost NS, Rothwell PM, Rotter JI, Rundek T, Sacco RL, Sakaue S, Sale MM, Salomaa V, Sapkota BR, Schmidt R, Schmidt… See abstract for full author list ➔ Malik R, et al. Among authors: mcardle pf. Nat Genet. 2018 Apr;50(4):524-537. doi: 10.1038/s41588-018-0058-3. Epub 2018 Mar 12. Nat Genet. 2018. PMID: 29531354 Free PMC article.
Phosphodiesterase 4D polymorphisms and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study.
Song Q, Cole JW, O'Connell JR, Stine OC, Gallagher M, Giles WH, Mitchell BD, Wozniak MA, Stern BJ, Sorkin JD, McArdle PF, Naj AC, Xu Q, Gibbons GH, Kittner SJ. Song Q, et al. Among authors: mcardle pf. Hum Mol Genet. 2006 Aug 15;15(16):2468-78. doi: 10.1093/hmg/ddl169. Epub 2006 Jul 11. Hum Mol Genet. 2006. PMID: 16835261 Free PMC article.
Genome-wide association scan identifies variants near Matrix Metalloproteinase (MMP) genes on chromosome 11q21-22 strongly associated with serum MMP-1 levels.
Cheng YC, Kao WH, Mitchell BD, O'Connell JR, Shen H, McArdle PF, Gibson Q, Ryan KA, Shuldiner AR, Pollin TI. Cheng YC, et al. Among authors: mcardle pf. Circ Cardiovasc Genet. 2009 Aug;2(4):329-37. doi: 10.1161/CIRCGENETICS.108.834986. Epub 2009 May 14. Circ Cardiovasc Genet. 2009. PMID: 20031604 Free PMC article.
165 results