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BLUEPRINT to decode the epigenetic signature written in blood.
Adams D, Altucci L, Antonarakis SE, Ballesteros J, Beck S, Bird A, Bock C, Boehm B, Campo E, Caricasole A, Dahl F, Dermitzakis ET, Enver T, Esteller M, Estivill X, Ferguson-Smith A, Fitzgibbon J, Flicek P, Giehl C, Graf T, Grosveld F, Guigo R, Gut I, Helin K, Jarvius J, Küppers R, Lehrach H, Lengauer T, Lernmark Å, Leslie D, Loeffler M, Macintyre E, Mai A, Martens JH, Minucci S, Ouwehand WH, Pelicci PG, Pendeville H, Porse B, Rakyan V, Reik W, Schrappe M, Schübeler D, Seifert M, Siebert R, Simmons D, Soranzo N, Spicuglia S, Stratton M, Stunnenberg HG, Tanay A, Torrents D, Valencia A, Vellenga E, Vingron M, Walter J, Willcocks S. Adams D, et al. Among authors: graf t. Nat Biotechnol. 2012 Mar 7;30(3):224-6. doi: 10.1038/nbt.2153. Nat Biotechnol. 2012. PMID: 22398613 No abstract available.
Forcing cells to change lineages.
Graf T, Enver T. Graf T, et al. Nature. 2009 Dec 3;462(7273):587-94. doi: 10.1038/nature08533. Nature. 2009. PMID: 19956253 Review.
CTCF chromatin residence time controls three-dimensional genome organization, gene expression and DNA methylation in pluripotent cells.
Soochit W, Sleutels F, Stik G, Bartkuhn M, Basu S, Hernandez SC, Merzouk S, Vidal E, Boers R, Boers J, van der Reijden M, Geverts B, van Cappellen WA, van den Hout M, Ozgur Z, van IJcken WFJ, Gribnau J, Renkawitz R, Graf T, Houtsmuller A, Grosveld F, Stadhouders R, Galjart N. Soochit W, et al. Among authors: graf t. Nat Cell Biol. 2021 Aug;23(8):881-893. doi: 10.1038/s41556-021-00722-w. Epub 2021 Jul 29. Nat Cell Biol. 2021. PMID: 34326481
Immunology: blood lines redrawn.
Graf T. Graf T. Nature. 2008 Apr 10;452(7188):702-3. doi: 10.1038/452702a. Nature. 2008. PMID: 18401396 No abstract available.
Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming.
Stadhouders R, Vidal E, Serra F, Di Stefano B, Le Dily F, Quilez J, Gomez A, Collombet S, Berenguer C, Cuartero Y, Hecht J, Filion GJ, Beato M, Marti-Renom MA, Graf T. Stadhouders R, et al. Among authors: graf t. Nat Genet. 2018 Feb;50(2):238-249. doi: 10.1038/s41588-017-0030-7. Epub 2018 Jan 15. Nat Genet. 2018. PMID: 29335546 Free PMC article.
Hoxb5, a Trojan horse to generate T cells.
Stik G, Graf T. Stik G, et al. Among authors: graf t. Nat Immunol. 2018 Mar;19(3):210-212. doi: 10.1038/s41590-018-0053-y. Nat Immunol. 2018. PMID: 29476186 No abstract available.
783 results