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The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure.
Yndestad A, Finsen AV, Ueland T, Husberg C, Dahl CP, Øie E, Vinge LE, Sjaastad I, Sandanger Ø, Ranheim T, Dickstein K, Kjekshus J, Damås JK, Fiane AE, Hilfiker-Kleiner D, Lipp M, Gullestad L, Christensen G, Aukrust P. Yndestad A, et al. Among authors: finsen av. PLoS One. 2012;7(3):e33038. doi: 10.1371/journal.pone.0033038. Epub 2012 Mar 12. PLoS One. 2012. PMID: 22427939 Free PMC article.
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload.
Waehre A, Halvorsen B, Yndestad A, Husberg C, Sjaastad I, Nygård S, Dahl CP, Ahmed MS, Finsen AV, Reims H, Louch WE, Hilfiker-Kleiner D, Vinge LE, Roald B, Attramadal H, Lipp M, Gullestad L, Aukrust P, Christensen G. Waehre A, et al. Among authors: finsen av. PLoS One. 2011 Apr 18;6(4):e18668. doi: 10.1371/journal.pone.0018668. PLoS One. 2011. PMID: 21533157 Free PMC article.
The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure.
Askevold ET, Aukrust P, Nymo SH, Lunde IG, Kaasbøll OJ, Aakhus S, Florholmen G, Ohm IK, Strand ME, Attramadal H, Fiane A, Dahl CP, Finsen AV, Vinge LE, Christensen G, Yndestad A, Gullestad L, Latini R, Masson S, Tavazzi L; GISSI-HF Investigators; Ueland T. Askevold ET, et al. Among authors: finsen av. J Intern Med. 2014 Jun;275(6):621-30. doi: 10.1111/joim.12175. Epub 2014 Jan 9. J Intern Med. 2014. PMID: 24330105 Free article.
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.
Sandanger Ø, Ranheim T, Vinge LE, Bliksøen M, Alfsnes K, Finsen AV, Dahl CP, Askevold ET, Florholmen G, Christensen G, Fitzgerald KA, Lien E, Valen G, Espevik T, Aukrust P, Yndestad A. Sandanger Ø, et al. Among authors: finsen av. Cardiovasc Res. 2013 Jul 1;99(1):164-74. doi: 10.1093/cvr/cvt091. Epub 2013 Apr 10. Cardiovasc Res. 2013. PMID: 23580606
Increased production of CXCL16 in experimental and clinical heart failure: a possible role in extracellular matrix remodeling.
Dahl CP, Husberg C, Gullestad L, Waehre A, Damås JK, Vinge LE, Finsen AV, Ueland T, Florholmen G, Aakhus S, Halvorsen B, Aukrust P, Oie E, Yndestad A, Christensen G. Dahl CP, et al. Among authors: finsen av. Circ Heart Fail. 2009 Nov;2(6):624-32. doi: 10.1161/CIRCHEARTFAILURE.108.821074. Epub 2009 Sep 22. Circ Heart Fail. 2009. PMID: 19919988
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