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The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure.
Yndestad A, Finsen AV, Ueland T, Husberg C, Dahl CP, Øie E, Vinge LE, Sjaastad I, Sandanger Ø, Ranheim T, Dickstein K, Kjekshus J, Damås JK, Fiane AE, Hilfiker-Kleiner D, Lipp M, Gullestad L, Christensen G, Aukrust P. Yndestad A, et al. PLoS One. 2012;7(3):e33038. doi: 10.1371/journal.pone.0033038. Epub 2012 Mar 12. PLoS One. 2012. PMID: 22427939 Free PMC article.
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload.
Waehre A, Halvorsen B, Yndestad A, Husberg C, Sjaastad I, Nygård S, Dahl CP, Ahmed MS, Finsen AV, Reims H, Louch WE, Hilfiker-Kleiner D, Vinge LE, Roald B, Attramadal H, Lipp M, Gullestad L, Aukrust P, Christensen G. Waehre A, et al. PLoS One. 2011 Apr 18;6(4):e18668. doi: 10.1371/journal.pone.0018668. PLoS One. 2011. PMID: 21533157 Free PMC article.
Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology.
Heymans S, Hirsch E, Anker SD, Aukrust P, Balligand JL, Cohen-Tervaert JW, Drexler H, Filippatos G, Felix SB, Gullestad L, Hilfiker-Kleiner D, Janssens S, Latini R, Neubauer G, Paulus WJ, Pieske B, Ponikowski P, Schroen B, Schultheiss HP, Tschöpe C, Van Bilsen M, Zannad F, McMurray J, Shah AM. Heymans S, et al. Eur J Heart Fail. 2009 Feb;11(2):119-29. doi: 10.1093/eurjhf/hfn043. Eur J Heart Fail. 2009. PMID: 19168509 Free PMC article. Review.
Acute heart failure: mechanisms and pre-clinical models-a Scientific Statement of the ESC Working Group on Myocardial Function.
Ciccarelli M, Pires IF, Bauersachs J, Bertrand L, Beauloye C, Dawson D, Hamdani N, Hilfiker-Kleiner D, van Laake LW, Lezoualc'h F, Linke WA, Lunde IG, Rainer PP, Rispoli A, Visco V, Carrizzo A, Ferro MD, Stolfo D, van der Velden J, Zacchigna S, Heymans S, Thum T, Tocchetti CG. Ciccarelli M, et al. Among authors: hilfiker kleiner d. Cardiovasc Res. 2023 Nov 15;119(14):2390-2404. doi: 10.1093/cvr/cvad088. Cardiovasc Res. 2023. PMID: 37967390
Many good reasons to have STAT3 in the heart.
Hilfiker-Kleiner D, Hilfiker A, Drexler H. Hilfiker-Kleiner D, et al. Pharmacol Ther. 2005 Jul;107(1):131-7. doi: 10.1016/j.pharmthera.2005.02.003. Epub 2005 Apr 21. Pharmacol Ther. 2005. PMID: 15963355 Review.
STAT3-mediated activation of myocardial capillary growth.
Hilfiker-Kleiner D, Limbourg A, Drexler H. Hilfiker-Kleiner D, et al. Trends Cardiovasc Med. 2005 May;15(4):152-7. doi: 10.1016/j.tcm.2005.05.002. Trends Cardiovasc Med. 2005. PMID: 16099380 Review.
230 results