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The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors.
Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6662-7. doi: 10.1073/pnas.1121623109. Epub 2012 Mar 26.
Proc Natl Acad Sci U S A. 2012.
PMID: 22451913
Free PMC article.
Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity.
Ring NG, Herndler-Brandstetter D, Weiskopf K, Shan L, Volkmer JP, George BM, Lietzenmayer M, McKenna KM, Naik TJ, McCarty A, Zheng Y, Ring AM, Flavell RA, Weissman IL.
Ring NG, et al. Among authors: naik tj.
Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):E10578-E10585. doi: 10.1073/pnas.1710877114. Epub 2017 Nov 20.
Proc Natl Acad Sci U S A. 2017.
PMID: 29158380
Free PMC article.
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Blockade of the erbB2 receptor induces cardiomyocyte death through mitochondrial and reactive oxygen species-dependent pathways.
Gordon LI, Burke MA, Singh AT, Prachand S, Lieberman ED, Sun L, Naik TJ, Prasad SV, Ardehali H.
Gordon LI, et al. Among authors: naik tj.
J Biol Chem. 2009 Jan 23;284(4):2080-7. doi: 10.1074/jbc.M804570200. Epub 2008 Nov 18.
J Biol Chem. 2009.
PMID: 19017630
Free PMC article.
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Glucose phosphorylation and mitochondrial binding are required for the protective effects of hexokinases I and II.
Sun L, Shukair S, Naik TJ, Moazed F, Ardehali H.
Sun L, et al. Among authors: naik tj.
Mol Cell Biol. 2008 Feb;28(3):1007-17. doi: 10.1128/MCB.00224-07. Epub 2007 Nov 26.
Mol Cell Biol. 2008.
PMID: 18039843
Free PMC article.
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Phosphorylation of contractile proteins in response to alpha- and beta-adrenergic stimulation in neonatal cardiomyocytes.
Decker RS, Rines AK, Nakamura S, Naik TJ, Wassertsrom JA, Ardehali H.
Decker RS, et al. Among authors: naik tj.
Transl Res. 2010 Jan;155(1):27-34. doi: 10.1016/j.trsl.2009.09.007.
Transl Res. 2010.
PMID: 20004359
Free PMC article.
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Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation.
Ichikawa Y, Ghanefar M, Bayeva M, Wu R, Khechaduri A, Naga Prasad SV, Mutharasan RK, Naik TJ, Ardehali H.
Ichikawa Y, et al. Among authors: naik tj.
J Clin Invest. 2014 Feb;124(2):617-30. doi: 10.1172/JCI72931. Epub 2014 Jan 2.
J Clin Invest. 2014.
PMID: 24382354
Free PMC article.
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