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Systematic identification of genomic markers of drug sensitivity in cancer cells.
Nature. 2012 Mar 28;483(7391):570-5. doi: 10.1038/nature11005.
Nature. 2012.
PMID: 22460902
Free PMC article.
Nilotinib and MEK inhibitors induce synthetic lethality through paradoxical activation of RAF in drug-resistant chronic myeloid leukemia.
Packer LM, Rana S, Hayward R, O'Hare T, Eide CA, Rebocho A, Heidorn S, Zabriskie MS, Niculescu-Duvaz I, Druker BJ, Springer C, Marais R.
Packer LM, et al.
Cancer Cell. 2011 Dec 13;20(6):715-27. doi: 10.1016/j.ccr.2011.11.004.
Cancer Cell. 2011.
PMID: 22169110
Free PMC article.
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Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.
Heidorn SJ, Milagre C, Whittaker S, Nourry A, Niculescu-Duvas I, Dhomen N, Hussain J, Reis-Filho JS, Springer CJ, Pritchard C, Marais R.
Heidorn SJ, et al.
Cell. 2010 Jan 22;140(2):209-21. doi: 10.1016/j.cell.2009.12.040.
Cell. 2010.
PMID: 20141835
Free PMC article.
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Raf inhibitors target ras spatiotemporal dynamics.
Cho KJ, Kasai RS, Park JH, Chigurupati S, Heidorn SJ, van der Hoeven D, Plowman SJ, Kusumi A, Marais R, Hancock JF.
Cho KJ, et al. Among authors: heidorn sj.
Curr Biol. 2012 Jun 5;22(11):945-55. doi: 10.1016/j.cub.2012.03.067. Epub 2012 May 3.
Curr Biol. 2012.
PMID: 22560614
Free article.
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Tnfaip8 is an essential gene for the regulation of glucocorticoid-mediated apoptosis of thymocytes.
Woodward MJ, de Boer J, Heidorn S, Hubank M, Kioussis D, Williams O, Brady HJ.
Woodward MJ, et al.
Cell Death Differ. 2010 Feb;17(2):316-23. doi: 10.1038/cdd.2009.125. Epub 2009 Sep 4.
Cell Death Differ. 2010.
PMID: 19730441
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