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A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.
Alimonti A, Nardella C, Chen Z, Clohessy JG, Carracedo A, Trotman LC, Cheng K, Varmeh S, Kozma SC, Thomas G, Rosivatz E, Woscholski R, Cognetti F, Scher HI, Pandolfi PP. Alimonti A, et al. Among authors: chen z. J Clin Invest. 2010 Mar;120(3):681-93. doi: 10.1172/JCI40535. Epub 2010 Feb 8. J Clin Invest. 2010. PMID: 20197621 Free PMC article.
Mouse models of prostate cancer: picking the best model for the question.
Grabowska MM, DeGraff DJ, Yu X, Jin RJ, Chen Z, Borowsky AD, Matusik RJ. Grabowska MM, et al. Among authors: chen z. Cancer Metastasis Rev. 2014 Sep;33(2-3):377-97. doi: 10.1007/s10555-013-9487-8. Cancer Metastasis Rev. 2014. PMID: 24452759 Free PMC article. Review.
Identifying actionable targets through integrative analyses of GEM model and human prostate cancer genomic profiling.
Wanjala J, Taylor BS, Chapinski C, Hieronymus H, Wongvipat J, Chen Y, Nanjangud GJ, Schultz N, Xie Y, Liu S, Lu W, Yang Q, Sander C, Chen Z, Sawyers CL, Carver BS. Wanjala J, et al. Among authors: chen z, chen y. Mol Cancer Ther. 2015 Jan;14(1):278-88. doi: 10.1158/1535-7163.MCT-14-0542-T. Epub 2014 Nov 7. Mol Cancer Ther. 2015. PMID: 25381262 Free PMC article.
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