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Page 1
Modeling serpin conformational diseases in Drosophila melanogaster.
Jahn TR, Malzer E, Roote J, Vishnivetskaya A, Imarisio S, Giannakou M, Panser K, Marciniak S, Crowther DC. Jahn TR, et al. Among authors: imarisio s. Methods Enzymol. 2011;499:227-58. doi: 10.1016/B978-0-12-386471-0.00012-2. Methods Enzymol. 2011. PMID: 21683257
Alpha-helix targeting reduces amyloid-beta peptide toxicity.
Nerelius C, Sandegren A, Sargsyan H, Raunak R, Leijonmarck H, Chatterjee U, Fisahn A, Imarisio S, Lomas DA, Crowther DC, Strömberg R, Johansson J. Nerelius C, et al. Among authors: imarisio s. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9191-6. doi: 10.1073/pnas.0810364106. Epub 2009 May 20. Proc Natl Acad Sci U S A. 2009. PMID: 19458258 Free PMC article.
CCT complex restricts neuropathogenic protein aggregation via autophagy.
Pavel M, Imarisio S, Menzies FM, Jimenez-Sanchez M, Siddiqi FH, Wu X, Renna M, O'Kane CJ, Crowther DC, Rubinsztein DC. Pavel M, et al. Among authors: imarisio s. Nat Commun. 2016 Dec 8;7:13821. doi: 10.1038/ncomms13821. Nat Commun. 2016. PMID: 27929117 Free PMC article.
Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity.
Menzies FM, Garcia-Arencibia M, Imarisio S, O'Sullivan NC, Ricketts T, Kent BA, Rao MV, Lam W, Green-Thompson ZW, Nixon RA, Saksida LM, Bussey TJ, O'Kane CJ, Rubinsztein DC. Menzies FM, et al. Among authors: imarisio s. Cell Death Differ. 2015 Mar;22(3):433-44. doi: 10.1038/cdd.2014.151. Epub 2014 Sep 26. Cell Death Differ. 2015. PMID: 25257175 Free PMC article.
α-Synuclein impairs macroautophagy: implications for Parkinson's disease.
Winslow AR, Chen CW, Corrochano S, Acevedo-Arozena A, Gordon DE, Peden AA, Lichtenberg M, Menzies FM, Ravikumar B, Imarisio S, Brown S, O'Kane CJ, Rubinsztein DC. Winslow AR, et al. Among authors: imarisio s. J Cell Biol. 2010 Sep 20;190(6):1023-37. doi: 10.1083/jcb.201003122. J Cell Biol. 2010. PMID: 20855506 Free PMC article.
siRNA screen identifies QPCT as a druggable target for Huntington's disease.
Jimenez-Sanchez M, Lam W, Hannus M, Sönnichsen B, Imarisio S, Fleming A, Tarditi A, Menzies F, Dami TE, Xu C, Gonzalez-Couto E, Lazzeroni G, Heitz F, Diamanti D, Massai L, Satagopam VP, Marconi G, Caramelli C, Nencini A, Andreini M, Sardone GL, Caradonna NP, Porcari V, Scali C, Schneider R, Pollio G, O'Kane CJ, Caricasole A, Rubinsztein DC. Jimenez-Sanchez M, et al. Among authors: imarisio s. Nat Chem Biol. 2015 May;11(5):347-354. doi: 10.1038/nchembio.1790. Epub 2015 Apr 6. Nat Chem Biol. 2015. PMID: 25848931 Free PMC article.
30 results