Luheshi LM - Search Results

1

Expression in drosophila of tandem amyloid β peptides provides insights into links between aggregation and neurotoxicity.

Speretta E, Jahn TR, Tartaglia GG, Favrin G, Barros TP, Imarisio S, Lomas DA, Luheshi LM, Crowther DC, Dobson CM. Speretta E, et al. Among authors: luheshi lm. J Biol Chem. 2012 Jun 8;287(24):20748-54. doi: 10.1074/jbc.M112.350124. Epub 2012 Mar 29. J Biol Chem. 2012. PMID: 22461632 Free PMC article.

2

Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity.

Luheshi LM, Tartaglia GG, Brorsson AC, Pawar AP, Watson IE, Chiti F, Vendruscolo M, Lomas DA, Dobson CM, Crowther DC. Luheshi LM, et al. PLoS Biol. 2007 Oct 30;5(11):e290. doi: 10.1371/journal.pbio.0050290. PLoS Biol. 2007. PMID: 17973577 Free PMC article.

3

Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo.

Luheshi LM, Hoyer W, de Barros TP, van Dijk Härd I, Brorsson AC, Macao B, Persson C, Crowther DC, Lomas DA, Ståhl S, Dobson CM, Härd T. Luheshi LM, et al. PLoS Biol. 2010 Mar 16;8(3):e1000334. doi: 10.1371/journal.pbio.1000334. PLoS Biol. 2010. PMID: 20305716 Free PMC article.

4

Intrinsic determinants of neurotoxic aggregate formation by the amyloid beta peptide.

Brorsson AC, Bolognesi B, Tartaglia GG, Shammas SL, Favrin G, Watson I, Lomas DA, Chiti F, Vendruscolo M, Dobson CM, Crowther DC, Luheshi LM. Brorsson AC, et al. Among authors: luheshi lm. Biophys J. 2010 Apr 21;98(8):1677-84. doi: 10.1016/j.bpj.2009.12.4320. Biophys J. 2010. PMID: 20409489 Free PMC article.

5

The aggregation and neurotoxicity of TDP-43 and its ALS-associated 25 kDa fragment are differentially affected by molecular chaperones in Drosophila.

Gregory JM, Barros TP, Meehan S, Dobson CM, Luheshi LM. Gregory JM, et al. Among authors: luheshi lm. PLoS One. 2012;7(2):e31899. doi: 10.1371/journal.pone.0031899. Epub 2012 Feb 22. PLoS One. 2012. PMID: 22384095 Free PMC article.

6

Direct observations of amyloid β self-assembly in live cells provide insights into differences in the kinetics of Aβ(1-40) and Aβ(1-42) aggregation.

Esbjörner EK, Chan F, Rees E, Erdelyi M, Luheshi LM, Bertoncini CW, Kaminski CF, Dobson CM, Kaminski Schierle GS. Esbjörner EK, et al. Among authors: luheshi lm. Chem Biol. 2014 Jun 19;21(6):732-42. doi: 10.1016/j.chembiol.2014.03.014. Epub 2014 May 22. Chem Biol. 2014. PMID: 24856820 Free PMC article.

7

Structural reorganisation and potential toxicity of oligomeric species formed during the assembly of amyloid fibrils.

Cheon M, Chang I, Mohanty S, Luheshi LM, Dobson CM, Vendruscolo M, Favrin G. Cheon M, et al. Among authors: luheshi lm. PLoS Comput Biol. 2007 Sep;3(9):1727-38. doi: 10.1371/journal.pcbi.0030173. PLoS Comput Biol. 2007. PMID: 17941703 Free PMC article.

8

Protein misfolding and disease: from the test tube to the organism.

Luheshi LM, Crowther DC, Dobson CM. Luheshi LM, et al. Curr Opin Chem Biol. 2008 Feb;12(1):25-31. doi: 10.1016/j.cbpa.2008.02.011. Epub 2008 Mar 18. Curr Opin Chem Biol. 2008. PMID: 18295611 Review.

9

Bridging the gap: from protein misfolding to protein misfolding diseases.

Luheshi LM, Dobson CM. Luheshi LM, et al. FEBS Lett. 2009 Aug 20;583(16):2581-6. doi: 10.1016/j.febslet.2009.06.030. Epub 2009 Jun 21. FEBS Lett. 2009. PMID: 19545568 Free article. Review.

10

Methods and models in neurodegenerative and systemic protein aggregation diseases.

Brorsson AC, Kumita JR, MacLeod I, Bolognesi B, Speretta E, Luheshi LM, Knowles TP, Dobson CM, Crowther DC. Brorsson AC, et al. Among authors: luheshi lm. Front Biosci (Landmark Ed). 2010 Jan 1;15(1):373-96. doi: 10.2741/3626. Front Biosci (Landmark Ed). 2010. PMID: 20036826 Free article. Review.

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