Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

141,172 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Steroidal C-21 heteroaryl thioethers. Part 3: pregn-4-eno-[3,2-c]pyrazole fused A ring modified steroids as selective glucocorticoid receptor modulators (dissociated steroids).
Biju P, Wang H, Anthes J, McCormick K, Aslanian R, Berlin M, Bitar R, Lim YH, Lee YJ, Prelusky D, Mcleod R, Jia Y, Fernandez X, Lieber G, Jimenez J, Eckel S, House A, Chapman R, Phillips J. Biju P, et al. Among authors: wang h. Bioorg Med Chem Lett. 2012 May 1;22(9):3291-5. doi: 10.1016/j.bmcl.2012.03.015. Epub 2012 Mar 11. Bioorg Med Chem Lett. 2012. PMID: 22465636
Steroidal C-21 heteroaryl thioethers (Part 2): discovery of orally bioavailable selective glucocorticoid receptor modulators (dissociated steroids).
Biju P, McCormick K, Aslanian R, Berlin M, Solomon D, Wang H, Lee YJ, Bitar R, Prelusky D, McLeod R, Jia Y, Fernandez X, Eckel S, House A, Lieber G, Jimenez J, Kelly G, Chapman R, Phillips J, Anthes J. Biju P, et al. Among authors: wang h. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1086-90. doi: 10.1016/j.bmcl.2011.11.120. Epub 2011 Dec 7. Bioorg Med Chem Lett. 2012. PMID: 22197391
Discovery of aminoquinazoline derivatives as human A(2A) adenosine receptor antagonists.
Zhou G, Aslanian R, Gallo G, Khan T, Kuang R, Purakkattle B, De Ruiz M, Stamford A, Ting P, Wu H, Wang H, Xiao D, Yu T, Zhang Y, Mullins D, Hodgson R. Zhou G, et al. Among authors: wang h. Bioorg Med Chem Lett. 2016 Feb 15;26(4):1348-54. doi: 10.1016/j.bmcl.2015.11.048. Epub 2015 Dec 1. Bioorg Med Chem Lett. 2016. PMID: 26781932
Cyclic urea derivatives as potent NK1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions.
Shue HJ, Chen X, Schwerdt JH, Paliwal S, Blythin DJ, Lin L, Gu D, Wang C, Reichard GA, Wang H, Piwinski JJ, Duffy RA, Lachowicz JE, Coffin VL, Nomeir AA, Morgan CA, Varty GB, Shih NY. Shue HJ, et al. Among authors: wang h, wang c. Bioorg Med Chem Lett. 2006 Feb 15;16(4):1065-9. doi: 10.1016/j.bmcl.2005.10.072. Epub 2005 Nov 14. Bioorg Med Chem Lett. 2006. PMID: 16290143
Diaryl piperidines as CB1 receptor antagonists.
Scott JD, Li SW, Wang H, Xia Y, Jayne CL, Miller MW, Duffy RA, Boykow GC, Kowalski TJ, Spar BD, Stamford AW, Chackalamannil S, Lachowicz JE, Greenlee WJ. Scott JD, et al. Among authors: wang h. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1278-83. doi: 10.1016/j.bmcl.2009.11.075. Epub 2009 Nov 20. Bioorg Med Chem Lett. 2010. PMID: 20018510
Iminopyrimidinones: a novel pharmacophore for the development of orally active renin inhibitors.
McKittrick BA, Caldwell JP, Bara T, Boykow G, Chintala M, Clader J, Czarniecki M, Courneya B, Duffy R, Fleming L, Giessert R, Greenlee WJ, Heap C, Hong L, Huang Y, Iserloh U, Josien H, Khan T, Korfmacher W, Liang X, Mazzola R, Mitra S, Moore K, Orth P, Rajagopalan M, Roy S, Sakwa S, Strickland C, Vaccaro H, Voigt J, Wang H, Wong J, Zhang R, Zych A. McKittrick BA, et al. Among authors: wang h. Bioorg Med Chem Lett. 2015 Apr 1;25(7):1592-6. doi: 10.1016/j.bmcl.2015.02.003. Epub 2015 Feb 10. Bioorg Med Chem Lett. 2015. PMID: 25728416
Design and discovery of C2-fluoroalkyl iminothiazine dioxides as BACE inhibitors.
Taoka BM, Wu WL, Hao J, Dolmaski M, Wang H, Levorse D, Orth P, Hyde LA, Smith B, Michener MS, Kennedy ME, Parker EM, Cumming JN. Taoka BM, et al. Among authors: wang h. Bioorg Med Chem Lett. 2022 Jan 15;56:128463. doi: 10.1016/j.bmcl.2021.128463. Epub 2021 Nov 24. Bioorg Med Chem Lett. 2022. PMID: 34838652
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates.
Mandal M, Wu Y, Misiaszek J, Li G, Buevich A, Caldwell JP, Liu X, Mazzola RD, Orth P, Strickland C, Voigt J, Wang H, Zhu Z, Chen X, Grzelak M, Hyde LA, Kuvelkar R, Leach PT, Terracina G, Zhang L, Zhang Q, Michener MS, Smith B, Cox K, Grotz D, Favreau L, Mitra K, Kazakevich I, McKittrick BA, Greenlee W, Kennedy ME, Parker EM, Cumming JN, Stamford AW. Mandal M, et al. Among authors: wang h. J Med Chem. 2016 Apr 14;59(7):3231-48. doi: 10.1021/acs.jmedchem.5b01995. Epub 2016 Mar 22. J Med Chem. 2016. PMID: 26937601
Design and validation of bicyclic iminopyrimidinones as beta amyloid cleaving enzyme-1 (BACE1) inhibitors: conformational constraint to favor a bioactive conformation.
Mandal M, Zhu Z, Cumming JN, Liu X, Strickland C, Mazzola RD, Caldwell JP, Leach P, Grzelak M, Hyde L, Zhang Q, Terracina G, Zhang L, Chen X, Kuvelkar R, Kennedy ME, Favreau L, Cox K, Orth P, Buevich A, Voigt J, Wang H, Kazakevich I, McKittrick BA, Greenlee W, Parker EM, Stamford AW. Mandal M, et al. Among authors: wang h. J Med Chem. 2012 Nov 8;55(21):9331-45. doi: 10.1021/jm301039c. Epub 2012 Oct 1. J Med Chem. 2012. PMID: 22989333
141,172 results
You have reached the last available page of results. Please see the User Guide for more information.