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Design, Synthesis and Biological Evaluation of 1,4-Benzenesulfonamide Derivatives as Glyoxalase I Inhibitors.
Drug Des Devel Ther. 2022 Mar 28;16:873-885. doi: 10.2147/DDDT.S356621. eCollection 2022.
Drug Des Devel Ther. 2022.
PMID: 35378924
Free PMC article.
Lead optimization and biological evaluation of diazenylbenzenesulfonamides inhibitors against glyoxalase-I enzyme as potential anticancer agents.
Al-Oudat BA, Al-Shar'i NA, Al-Balas QA, Audat SA, Alqudah MAY, Hamzah AH, Hallak RW, Bedi M, Bryant-Friedrich A.
Al-Oudat BA, et al.
Bioorg Chem. 2022 Mar;120:105657. doi: 10.1016/j.bioorg.2022.105657. Epub 2022 Feb 5.
Bioorg Chem. 2022.
PMID: 35152183
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Design, synthesis and biological evaluation of novel glyoxalase I inhibitors possessing diazenylbenzenesulfonamide moiety as potential anticancer agents.
Al-Oudat BA, Jaradat HM, Al-Balas QA, Al-Shar'i NA, Bryant-Friedrich A, Bedi MF.
Al-Oudat BA, et al.
Bioorg Med Chem. 2020 Aug 15;28(16):115608. doi: 10.1016/j.bmc.2020.115608. Epub 2020 Jul 4.
Bioorg Med Chem. 2020.
PMID: 32690268
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Novel Chrysin-De-Allyl PAC-1 Hybrid Analogues as Anticancer Compounds: Design, Synthesis, and Biological Evaluation.
Al-Oudat BA, Ramapuram H, Malla S, Audat SA, Hussein N, Len JM, Kumari S, Bedi MF, Ashby CR Jr, Tiwari AK.
Al-Oudat BA, et al.
Molecules. 2020 Jul 4;25(13):3063. doi: 10.3390/molecules25133063.
Molecules. 2020.
PMID: 32635530
Free PMC article.
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Identification of Human Leukotriene A4 Hydrolase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking.
Audat SA, Al-Shar'i NA, Al-Oudat BA, Bryant-Friedrich A, Bedi MF, Zayed AL, Al-Balas QA.
Audat SA, et al. Among authors: al oudat ba.
Molecules. 2020 Jun 22;25(12):2871. doi: 10.3390/molecules25122871.
Molecules. 2020.
PMID: 32580506
Free PMC article.
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Design, synthesis, and biologic evaluation of novel chrysin derivatives as cytotoxic agents and caspase-3/7 activators.
Al-Oudat BA, Alqudah MA, Audat SA, Al-Balas QA, El-Elimat T, Hassan MA, Frhat IN, Azaizeh MM.
Al-Oudat BA, et al.
Drug Des Devel Ther. 2019 Jan 22;13:423-433. doi: 10.2147/DDDT.S189476. eCollection 2019.
Drug Des Devel Ther. 2019.
PMID: 30774307
Free PMC article.
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Synthesis of C3' modified nucleosides for selective generation of the C3'-deoxy-3'-thymidinyl radical: a proposed intermediate in LEE induced DNA damage.
Audat SA, Love CT, Al-Oudat BA, Bryant-Friedrich AC.
Audat SA, et al. Among authors: al oudat ba.
J Org Chem. 2012 Apr 20;77(8):3829-37. doi: 10.1021/jo300045m. Epub 2012 Apr 11.
J Org Chem. 2012.
PMID: 22468713
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