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Decreased extra-renal urate excretion is a common cause of hyperuricemia.
Ichida K, Matsuo H, Takada T, Nakayama A, Murakami K, Shimizu T, Yamanashi Y, Kasuga H, Nakashima H, Nakamura T, Takada Y, Kawamura Y, Inoue H, Okada C, Utsumi Y, Ikebuchi Y, Ito K, Nakamura M, Shinohara Y, Hosoyamada M, Sakurai Y, Shinomiya N, Hosoya T, Suzuki H. Ichida K, et al. Among authors: ito k. Nat Commun. 2012 Apr 3;3:764. doi: 10.1038/ncomms1756. Nat Commun. 2012. PMID: 22473008 Free PMC article.
Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2).
Sasaki M, Suzuki H, Ito K, Abe T, Sugiyama Y. Sasaki M, et al. Among authors: ito k. J Biol Chem. 2002 Feb 22;277(8):6497-503. doi: 10.1074/jbc.M109081200. Epub 2001 Dec 17. J Biol Chem. 2002. PMID: 11748225 Free article.
Prediction of in vivo biliary clearance from the in vitro transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II monolayer expressing both rat organic anion transporting polypeptide 4 and multidrug resistance associated protein 2.
Sasaki M, Suzuki H, Aoki J, Ito K, Meier PJ, Sugiyama Y. Sasaki M, et al. Among authors: ito k. Mol Pharmacol. 2004 Sep;66(3):450-9. doi: 10.1124/mol.66.3.. Mol Pharmacol. 2004. PMID: 15322236
Posttranslational regulation of Abcc2 expression by SUMOylation system.
Minami S, Ito K, Honma M, Ikebuchi Y, Anzai N, Kanai Y, Nishida T, Tsukita S, Sekine S, Horie T, Suzuki H. Minami S, et al. Among authors: ito k. Am J Physiol Gastrointest Liver Physiol. 2009 Feb;296(2):G406-13. doi: 10.1152/ajpgi.90309.2008. Epub 2008 Dec 12. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19074644 Free article.
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