Farooqi IS - Search Results

1

Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery.

Hatoum IJ, Stylopoulos N, Vanhoose AM, Boyd KL, Yin DP, Ellacott KL, Ma LL, Blaszczyk K, Keogh JM, Cone RD, Farooqi IS, Kaplan LM. Hatoum IJ, et al. Among authors: farooqi is. J Clin Endocrinol Metab. 2012 Jun;97(6):E1023-31. doi: 10.1210/jc.2011-3432. Epub 2012 Apr 6. J Clin Endocrinol Metab. 2012. PMID: 22492873 Free PMC article.

2

Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency.

Farooqi IS, Yeo GS, Keogh JM, Aminian S, Jebb SA, Butler G, Cheetham T, O'Rahilly S. Farooqi IS, et al. J Clin Invest. 2000 Jul;106(2):271-9. doi: 10.1172/JCI9397. J Clin Invest. 2000. PMID: 10903343 Free PMC article.

3

A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism.

Challis BG, Pritchard LE, Creemers JW, Delplanque J, Keogh JM, Luan J, Wareham NJ, Yeo GS, Bhattacharyya S, Froguel P, White A, Farooqi IS, O'Rahilly S. Challis BG, et al. Among authors: farooqi is. Hum Mol Genet. 2002 Aug 15;11(17):1997-2004. doi: 10.1093/hmg/11.17.1997. Hum Mol Genet. 2002. PMID: 12165561

4

Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.

Farooqi IS, Matarese G, Lord GM, Keogh JM, Lawrence E, Agwu C, Sanna V, Jebb SA, Perna F, Fontana S, Lechler RI, DePaoli AM, O'Rahilly S. Farooqi IS, et al. J Clin Invest. 2002 Oct;110(8):1093-103. doi: 10.1172/JCI15693. J Clin Invest. 2002. PMID: 12393845 Free PMC article.

5

Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms.

Yeo GS, Lank EJ, Farooqi IS, Keogh J, Challis BG, O'Rahilly S. Yeo GS, et al. Among authors: farooqi is. Hum Mol Genet. 2003 Mar 1;12(5):561-74. doi: 10.1093/hmg/ddg057. Hum Mol Genet. 2003. PMID: 12588803

6

Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene.

Farooqi IS, Keogh JM, Yeo GS, Lank EJ, Cheetham T, O'Rahilly S. Farooqi IS, et al. N Engl J Med. 2003 Mar 20;348(12):1085-95. doi: 10.1056/NEJMoa022050. N Engl J Med. 2003. PMID: 12646665 Free article.

7

Studies of the neuromedin U-2 receptor gene in human obesity: evidence for the existence of two ancestral forms of the receptor.

Bhattacharyya S, Luan J, Farooqi IS, Keogh J, Montague C, Brennand J, Jorde L, Wareham NJ, O'Rahilly S. Bhattacharyya S, et al. Among authors: farooqi is. J Endocrinol. 2004 Oct;183(1):115-20. doi: 10.1677/joe.1.05830. J Endocrinol. 2004. PMID: 15525579

8

A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance.

Lee YS, Challis BG, Thompson DA, Yeo GS, Keogh JM, Madonna ME, Wraight V, Sims M, Vatin V, Meyre D, Shield J, Burren C, Ibrahim Z, Cheetham T, Swift P, Blackwood A, Hung CC, Wareham NJ, Froguel P, Millhauser GL, O'Rahilly S, Farooqi IS. Lee YS, et al. Among authors: farooqi is. Cell Metab. 2006 Feb;3(2):135-40. doi: 10.1016/j.cmet.2006.01.006. Cell Metab. 2006. PMID: 16459314 Free article.

9

Heterozygosity for a POMC-null mutation and increased obesity risk in humans.

Farooqi IS, Drop S, Clements A, Keogh JM, Biernacka J, Lowenbein S, Challis BG, O'Rahilly S. Farooqi IS, et al. Diabetes. 2006 Sep;55(9):2549-53. doi: 10.2337/db06-0214. Diabetes. 2006. PMID: 16936203

10

Hyperphagia and early-onset obesity due to a novel homozygous missense mutation in prohormone convertase 1/3.

Farooqi IS, Volders K, Stanhope R, Heuschkel R, White A, Lank E, Keogh J, O'Rahilly S, Creemers JW. Farooqi IS, et al. J Clin Endocrinol Metab. 2007 Sep;92(9):3369-73. doi: 10.1210/jc.2007-0687. Epub 2007 Jun 26. J Clin Endocrinol Metab. 2007. PMID: 17595246

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