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Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways.
Widiapradja A, Vegh V, Lok KZ, Manzanero S, Thundyil J, Gelderblom M, Cheng YL, Pavlovski D, Tang SC, Jo DG, Magnus T, Chan SL, Sobey CG, Reutens D, Basta M, Mattson MP, Arumugam TV. Widiapradja A, et al. Among authors: gelderblom m. J Neurochem. 2012 Jul;122(2):321-32. doi: 10.1111/j.1471-4159.2012.07754.x. Epub 2012 Apr 27. J Neurochem. 2012. PMID: 22494053 Free PMC article.
Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke.
Arumugam TV, Cheng YL, Choi Y, Choi YH, Yang S, Yun YK, Park JS, Yang DK, Thundyil J, Gelderblom M, Karamyan VT, Tang SC, Chan SL, Magnus T, Sobey CG, Jo DG. Arumugam TV, et al. Among authors: gelderblom m. Mol Pharmacol. 2011 Jul;80(1):23-31. doi: 10.1124/mol.111.071076. Epub 2011 Mar 30. Mol Pharmacol. 2011. PMID: 21450930
Calorie restriction and stroke.
Manzanero S, Gelderblom M, Magnus T, Arumugam TV. Manzanero S, et al. Among authors: gelderblom m. Exp Transl Stroke Med. 2011 Sep 12;3:8. doi: 10.1186/2040-7378-3-8. Exp Transl Stroke Med. 2011. PMID: 21910904 Free PMC article.
The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice.
Gelderblom M, Leypoldt F, Lewerenz J, Birkenmayer G, Orozco D, Ludewig P, Thundyil J, Arumugam TV, Gerloff C, Tolosa E, Maher P, Magnus T. Gelderblom M, et al. J Cereb Blood Flow Metab. 2012 May;32(5):835-43. doi: 10.1038/jcbfm.2011.189. Epub 2012 Jan 11. J Cereb Blood Flow Metab. 2012. PMID: 22234339 Free PMC article.
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, Orthey E, Arumugam TV, Leypoldt F, Simova O, Thom V, Friese MA, Prinz I, Hölscher C, Glatzel M, Korn T, Gerloff C, Tolosa E, Magnus T. Gelderblom M, et al. Blood. 2012 Nov 1;120(18):3793-802. doi: 10.1182/blood-2012-02-412726. Epub 2012 Sep 13. Blood. 2012. PMID: 22976954 Free article.
90 results