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Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways.
Widiapradja A, Vegh V, Lok KZ, Manzanero S, Thundyil J, Gelderblom M, Cheng YL, Pavlovski D, Tang SC, Jo DG, Magnus T, Chan SL, Sobey CG, Reutens D, Basta M, Mattson MP, Arumugam TV. Widiapradja A, et al. J Neurochem. 2012 Jul;122(2):321-32. doi: 10.1111/j.1471-4159.2012.07754.x. Epub 2012 Apr 27. J Neurochem. 2012. PMID: 22494053 Free PMC article.
Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke.
Fann DY, Lee SY, Manzanero S, Tang SC, Gelderblom M, Chunduri P, Bernreuther C, Glatzel M, Cheng YL, Thundyil J, Widiapradja A, Lok KZ, Foo SL, Wang YC, Li YI, Drummond GR, Basta M, Magnus T, Jo DG, Mattson MP, Sobey CG, Arumugam TV. Fann DY, et al. Among authors: widiapradja a. Cell Death Dis. 2013 Sep 5;4(9):e790. doi: 10.1038/cddis.2013.326. Cell Death Dis. 2013. PMID: 24008734 Free PMC article.
Evidence that the EphA2 receptor exacerbates ischemic brain injury.
Thundyil J, Manzanero S, Pavlovski D, Cully TR, Lok KZ, Widiapradja A, Chunduri P, Jo DG, Naruse C, Asano M, Launikonis BS, Sobey CG, Coulthard MG, Arumugam TV. Thundyil J, et al. Among authors: widiapradja a. PLoS One. 2013;8(1):e53528. doi: 10.1371/journal.pone.0053528. Epub 2013 Jan 7. PLoS One. 2013. PMID: 23308246 Free PMC article.
Intermittent fasting attenuates inflammasome activity in ischemic stroke.
Fann DY, Santro T, Manzanero S, Widiapradja A, Cheng YL, Lee SY, Chunduri P, Jo DG, Stranahan AM, Mattson MP, Arumugam TV. Fann DY, et al. Among authors: widiapradja a. Exp Neurol. 2014 Jul;257:114-9. doi: 10.1016/j.expneurol.2014.04.017. Epub 2014 May 5. Exp Neurol. 2014. PMID: 24805069
Evidence for a detrimental role of TLR8 in ischemic stroke.
Tang SC, Yeh SJ, Li YI, Wang YC, Baik SH, Santro T, Widiapradja A, Manzanero S, Sobey CG, Jo DG, Arumugam TV, Jeng JS. Tang SC, et al. Among authors: widiapradja a. Exp Neurol. 2013 Dec;250:341-7. doi: 10.1016/j.expneurol.2013.10.012. Epub 2013 Oct 24. Exp Neurol. 2013. PMID: 24196452
17 results