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253 results

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Page 1
The clonal and mutational evolution spectrum of primary triple-negative breast cancers.
Shah SP, Roth A, Goya R, Oloumi A, Ha G, Zhao Y, Turashvili G, Ding J, Tse K, Haffari G, Bashashati A, Prentice LM, Khattra J, Burleigh A, Yap D, Bernard V, McPherson A, Shumansky K, Crisan A, Giuliany R, Heravi-Moussavi A, Rosner J, Lai D, Birol I, Varhol R, Tam A, Dhalla N, Zeng T, Ma K, Chan SK, Griffith M, Moradian A, Cheng SW, Morin GB, Watson P, Gelmon K, Chia S, Chin SF, Curtis C, Rueda OM, Pharoah PD, Damaraju S, Mackey J, Hoon K, Harkins T, Tadigotla V, Sigaroudinia M, Gascard P, Tlsty T, Costello JF, Meyer IM, Eaves CJ, Wasserman WW, Jones S, Huntsman D, Hirst M, Caldas C, Marra MA, Aparicio S. Shah SP, et al. Among authors: costello jf. Nature. 2012 Apr 4;486(7403):395-9. doi: 10.1038/nature10933. Nature. 2012. PMID: 22495314 Free PMC article.
Conserved role of intragenic DNA methylation in regulating alternative promoters.
Maunakea AK, Nagarajan RP, Bilenky M, Ballinger TJ, D'Souza C, Fouse SD, Johnson BE, Hong C, Nielsen C, Zhao Y, Turecki G, Delaney A, Varhol R, Thiessen N, Shchors K, Heine VM, Rowitch DH, Xing X, Fiore C, Schillebeeckx M, Jones SJ, Haussler D, Marra MA, Hirst M, Wang T, Costello JF. Maunakea AK, et al. Among authors: costello jf. Nature. 2010 Jul 8;466(7303):253-7. doi: 10.1038/nature09165. Nature. 2010. PMID: 20613842 Free PMC article.
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications.
Harris RA, Wang T, Coarfa C, Nagarajan RP, Hong C, Downey SL, Johnson BE, Fouse SD, Delaney A, Zhao Y, Olshen A, Ballinger T, Zhou X, Forsberg KJ, Gu J, Echipare L, O'Geen H, Lister R, Pelizzola M, Xi Y, Epstein CB, Bernstein BE, Hawkins RD, Ren B, Chung WY, Gu H, Bock C, Gnirke A, Zhang MQ, Haussler D, Ecker JR, Li W, Farnham PJ, Waterland RA, Meissner A, Marra MA, Hirst M, Milosavljevic A, Costello JF. Harris RA, et al. Among authors: costello jf. Nat Biotechnol. 2010 Oct;28(10):1097-105. doi: 10.1038/nbt.1682. Epub 2010 Sep 19. Nat Biotechnol. 2010. PMID: 20852635 Free PMC article.
The NIH Roadmap Epigenomics Mapping Consortium.
Bernstein BE, Stamatoyannopoulos JA, Costello JF, Ren B, Milosavljevic A, Meissner A, Kellis M, Marra MA, Beaudet AL, Ecker JR, Farnham PJ, Hirst M, Lander ES, Mikkelsen TS, Thomson JA. Bernstein BE, et al. Among authors: costello jf. Nat Biotechnol. 2010 Oct;28(10):1045-8. doi: 10.1038/nbt1010-1045. Nat Biotechnol. 2010. PMID: 20944595 Free PMC article.
Spark: a navigational paradigm for genomic data exploration.
Nielsen CB, Younesy H, O'Geen H, Xu X, Jackson AR, Milosavljevic A, Wang T, Costello JF, Hirst M, Farnham PJ, Jones SJ. Nielsen CB, et al. Among authors: costello jf. Genome Res. 2012 Nov;22(11):2262-9. doi: 10.1101/gr.140665.112. Epub 2012 Sep 7. Genome Res. 2012. PMID: 22960372 Free PMC article.
DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape.
Xie M, Hong C, Zhang B, Lowdon RF, Xing X, Li D, Zhou X, Lee HJ, Maire CL, Ligon KL, Gascard P, Sigaroudinia M, Tlsty TD, Kadlecek T, Weiss A, O'Geen H, Farnham PJ, Madden PA, Mungall AJ, Tam A, Kamoh B, Cho S, Moore R, Hirst M, Marra MA, Costello JF, Wang T. Xie M, et al. Among authors: costello jf. Nat Genet. 2013 Jul;45(7):836-41. doi: 10.1038/ng.2649. Epub 2013 May 26. Nat Genet. 2013. PMID: 23708189 Free PMC article.
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm.
Zhang B, Zhou Y, Lin N, Lowdon RF, Hong C, Nagarajan RP, Cheng JB, Li D, Stevens M, Lee HJ, Xing X, Zhou J, Sundaram V, Elliott G, Gu J, Shi T, Gascard P, Sigaroudinia M, Tlsty TD, Kadlecek T, Weiss A, O'Geen H, Farnham PJ, Maire CL, Ligon KL, Madden PA, Tam A, Moore R, Hirst M, Marra MA, Zhang B, Costello JF, Wang T. Zhang B, et al. Among authors: costello jf. Genome Res. 2013 Sep;23(9):1522-40. doi: 10.1101/gr.156539.113. Epub 2013 Jun 26. Genome Res. 2013. PMID: 23804400 Free PMC article.
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.
Johnson BE, Mazor T, Hong C, Barnes M, Aihara K, McLean CY, Fouse SD, Yamamoto S, Ueda H, Tatsuno K, Asthana S, Jalbert LE, Nelson SJ, Bollen AW, Gustafson WC, Charron E, Weiss WA, Smirnov IV, Song JS, Olshen AB, Cha S, Zhao Y, Moore RA, Mungall AJ, Jones SJM, Hirst M, Marra MA, Saito N, Aburatani H, Mukasa A, Berger MS, Chang SM, Taylor BS, Costello JF. Johnson BE, et al. Among authors: costello jf. Science. 2014 Jan 10;343(6167):189-193. doi: 10.1126/science.1239947. Epub 2013 Dec 12. Science. 2014. PMID: 24336570 Free PMC article.
ALEA: a toolbox for allele-specific epigenomics analysis.
Younesy H, Möller T, Heravi-Moussavi A, Cheng JB, Costello JF, Lorincz MC, Karimi MM, Jones SJ. Younesy H, et al. Among authors: costello jf. Bioinformatics. 2014 Apr 15;30(8):1172-1174. doi: 10.1093/bioinformatics/btt744. Epub 2013 Dec 26. Bioinformatics. 2014. PMID: 24371156
Regulatory network decoded from epigenomes of surface ectoderm-derived cell types.
Lowdon RF, Zhang B, Bilenky M, Mauro T, Li D, Gascard P, Sigaroudinia M, Farnham PJ, Bastian BC, Tlsty TD, Marra MA, Hirst M, Costello JF, Wang T, Cheng JB. Lowdon RF, et al. Among authors: costello jf. Nat Commun. 2014 Nov 25;5:5442. doi: 10.1038/ncomms6442. Nat Commun. 2014. PMID: 25421844 Free PMC article.
253 results