Westerman B - Search Results

1

Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer.

Nacerddine K, Beaudry JB, Ginjala V, Westerman B, Mattiroli F, Song JY, van der Poel H, Ponz OB, Pritchard C, Cornelissen-Steijger P, Zevenhoven J, Tanger E, Sixma TK, Ganesan S, van Lohuizen M. Nacerddine K, et al. Among authors: westerman b. J Clin Invest. 2012 May;122(5):1920-32. doi: 10.1172/JCI57477. Epub 2012 Apr 16. J Clin Invest. 2012. PMID: 22505453 Free PMC article.

2

Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion.

Michael LE, Westerman BA, Ermilov AN, Wang A, Ferris J, Liu J, Blom M, Ellison DW, van Lohuizen M, Dlugosz AA. Michael LE, et al. Neoplasia. 2008 Dec;10(12):1343-9, 5p following 1349. doi: 10.1593/neo.81078. Neoplasia. 2008. PMID: 19048113 Free PMC article.

3

A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation.

Westerman BA, Braat AK, Taub N, Potman M, Vissers JH, Blom M, Verhoeven E, Stoop H, Gillis A, Velds A, Nijkamp W, Beijersbergen R, Huber LA, Looijenga LH, van Lohuizen M. Westerman BA, et al. J Exp Med. 2011 Dec 19;208(13):2675-89. doi: 10.1084/jem.20102037. Epub 2011 Dec 5. J Exp Med. 2011. PMID: 22143885 Free PMC article.

4

GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors.

Westerman BA, Blom M, Tanger E, van der Valk M, Song JY, van Santen M, Gadiot J, Cornelissen-Steijger P, Zevenhoven J, Prosser HM, Uren A, Aronica E, van Lohuizen M. Westerman BA, et al. PLoS One. 2012;7(5):e35943. doi: 10.1371/journal.pone.0035943. Epub 2012 May 4. PLoS One. 2012. PMID: 22574128 Free PMC article.

5

A new transgenic mouse model for conditional overexpression of the Polycomb Group protein EZH2.

Koppens MA, Tanger E, Nacerddine K, Westerman B, Song JY, van Lohuizen M. Koppens MA, et al. Among authors: westerman b. Transgenic Res. 2017 Apr;26(2):187-196. doi: 10.1007/s11248-016-9993-x. Epub 2016 Nov 2. Transgenic Res. 2017. PMID: 27807665

6

miR-129-3p controls centrosome number in metastatic prostate cancer cells by repressing CP110.

Bijnsdorp IV, Hodzic J, Lagerweij T, Westerman B, Krijgsman O, Broeke J, Verweij F, Nilsson RJ, Rozendaal L, van Beusechem VW, van Moorselaar JA, Wurdinger T, Geldof AA. Bijnsdorp IV, et al. Among authors: westerman b. Oncotarget. 2016 Mar 29;7(13):16676-87. doi: 10.18632/oncotarget.7572. Oncotarget. 2016. PMID: 26918338 Free PMC article.

7

The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures.

Narayan RS, Fedrigo CA, Brands E, Dik R, Stalpers LJ, Baumert BG, Slotman BJ, Westerman BA, Peters GJ, Sminia P. Narayan RS, et al. BMC Cancer. 2017 Mar 21;17(1):204. doi: 10.1186/s12885-017-3193-9. BMC Cancer. 2017. PMID: 28320338 Free PMC article.

8

Detection of chromosome 21-encoded mRNA of placental origin in maternal plasma.

Oudejans CB, Go AT, Visser A, Mulders MA, Westerman BA, Blankenstein MA, van Vugt JM. Oudejans CB, et al. Among authors: westerman ba. Clin Chem. 2003 Sep;49(9):1445-9. doi: 10.1373/49.9.1445. Clin Chem. 2003. PMID: 12928224

9

Blood-brain barrier crossing and breakthroughs in glioblastoma therapy.

Sminia P, Westerman BA. Sminia P, et al. Among authors: westerman ba. Br J Clin Pharmacol. 2016 Jun;81(6):1018-20. doi: 10.1111/bcp.12881. Epub 2016 Feb 8. Br J Clin Pharmacol. 2016. PMID: 26744058 Free PMC article. No abstract available.

10

The TICking clock of EGFR therapy resistance in glioblastoma: Target Independence or target Compensation.

Saleem H, Kulsoom Abdul U, Küçükosmanoglu A, Houweling M, Cornelissen FMG, Heiland DH, Hegi ME, Kouwenhoven MCM, Bailey D, Würdinger T, Westerman BA. Saleem H, et al. Drug Resist Updat. 2019 Mar;43:29-37. doi: 10.1016/j.drup.2019.04.002. Epub 2019 Apr 22. Drug Resist Updat. 2019. PMID: 31054489 Free article.

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