van Lohuizen M - Search Results

1

Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer.

Nacerddine K, Beaudry JB, Ginjala V, Westerman B, Mattiroli F, Song JY, van der Poel H, Ponz OB, Pritchard C, Cornelissen-Steijger P, Zevenhoven J, Tanger E, Sixma TK, Ganesan S, van Lohuizen M. Nacerddine K, et al. Among authors: van der poel h, van lohuizen m. J Clin Invest. 2012 May;122(5):1920-32. doi: 10.1172/JCI57477. Epub 2012 Apr 16. J Clin Invest. 2012. PMID: 22505453 Free PMC article.

2

Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex.

Alkema MJ, Bronk M, Verhoeven E, Otte A, van 't Veer LJ, Berns A, van Lohuizen M. Alkema MJ, et al. Among authors: van t veer lj, van lohuizen m. Genes Dev. 1997 Jan 15;11(2):226-40. doi: 10.1101/gad.11.2.226. Genes Dev. 1997. PMID: 9009205 Free article.

3

Pertubation of B and T cell development and predisposition to lymphomagenesis in Emu Bmi1 transgenic mice require the Bmi1 RING finger.

Alkema MJ, Jacobs H, van Lohuizen M, Berns A. Alkema MJ, et al. Among authors: van lohuizen m. Oncogene. 1997 Aug 18;15(8):899-910. doi: 10.1038/sj.onc.1201262. Oncogene. 1997. PMID: 9285685

4

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

Jacobs JJ, Scheijen B, Voncken JW, Kieboom K, Berns A, van Lohuizen M. Jacobs JJ, et al. Among authors: van lohuizen m. Genes Dev. 1999 Oct 15;13(20):2678-90. doi: 10.1101/gad.13.20.2678. Genes Dev. 1999. PMID: 10541554 Free PMC article.

5

Chromatin-association of the Polycomb group protein BMI1 is cell cycle-regulated and correlates with its phosphorylation status.

Voncken JW, Schweizer D, Aagaard L, Sattler L, Jantsch MF, van Lohuizen M. Voncken JW, et al. Among authors: van lohuizen m. J Cell Sci. 1999 Dec;112 ( Pt 24):4627-39. doi: 10.1242/jcs.112.24.4627. J Cell Sci. 1999. PMID: 10574711

6

Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas.

Leung C, Lingbeek M, Shakhova O, Liu J, Tanger E, Saremaslani P, Van Lohuizen M, Marino S. Leung C, et al. Among authors: van lohuizen m. Nature. 2004 Mar 18;428(6980):337-41. doi: 10.1038/nature02385. Nature. 2004. PMID: 15029199

7

Stem cells and cancer; the polycomb connection.

Valk-Lingbeek ME, Bruggeman SW, van Lohuizen M. Valk-Lingbeek ME, et al. Among authors: van lohuizen m. Cell. 2004 Aug 20;118(4):409-18. doi: 10.1016/j.cell.2004.08.005. Cell. 2004. PMID: 15315754 Free article. Review.

8

Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase.

Hernández-Muñoz I, Lund AH, van der Stoop P, Boutsma E, Muijrers I, Verhoeven E, Nusinow DA, Panning B, Marahrens Y, van Lohuizen M. Hernández-Muñoz I, et al. Among authors: van der stoop p, van lohuizen m. Proc Natl Acad Sci U S A. 2005 May 24;102(21):7635-40. doi: 10.1073/pnas.0408918102. Epub 2005 May 16. Proc Natl Acad Sci U S A. 2005. PMID: 15897469 Free PMC article.

9

Bmi1 loss produces an increase in astroglial cells and a decrease in neural stem cell population and proliferation.

Zencak D, Lingbeek M, Kostic C, Tekaya M, Tanger E, Hornfeld D, Jaquet M, Munier FL, Schorderet DF, van Lohuizen M, Arsenijevic Y. Zencak D, et al. Among authors: van lohuizen m. J Neurosci. 2005 Jun 15;25(24):5774-83. doi: 10.1523/JNEUROSCI.3452-04.2005. J Neurosci. 2005. PMID: 15958744 Free PMC article.

10

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.

Bruggeman SW, Valk-Lingbeek ME, van der Stoop PP, Jacobs JJ, Kieboom K, Tanger E, Hulsman D, Leung C, Arsenijevic Y, Marino S, van Lohuizen M. Bruggeman SW, et al. Among authors: van der stoop pp, van lohuizen m. Genes Dev. 2005 Jun 15;19(12):1438-43. doi: 10.1101/gad.1299305. Genes Dev. 2005. PMID: 15964995 Free PMC article.

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