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TNNT2 mutations in the tropomyosin binding region of TNT1 disrupt its role in contractile inhibition and stimulate cardiac dysfunction.
Madan A, Viswanathan MC, Woulfe KC, Schmidt W, Sidor A, Liu T, Nguyen TH, Trinh B, Wilson C, Madathil S, Vogler G, O'Rourke B, Biesiadecki BJ, Tobacman LS, Cammarato A. Madan A, et al. Among authors: tobacman ls. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18822-18831. doi: 10.1073/pnas.2001692117. Epub 2020 Jul 20. Proc Natl Acad Sci U S A. 2020. PMID: 32690703 Free PMC article.
Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS).
CTSA Principal Investigators; Shamoon H, Center D, Davis P, Tuchman M, Ginsberg H, Califf R, Stephens D, Mellman T, Verbalis J, Nadler L, Shekhar A, Ford D, Rizza R, Shaker R, Brady K, Murphy B, Cronstein B, Hochman J, Greenland P, Orwoll E, Sinoway L, Greenberg H, Jackson R, Coller B, Topol E, Guay-Woodford L, Runge M, Clark R, McClain D, Selker H, Lowery C, Dubinett S, Berglund L, Cooper D, Firestein G, Johnston SC, Solway J, Heubi J, Sokol R, Nelson D, Tobacman L, Rosenthal G, Aaronson L, Barohn R, Kern P, Sullivan J, Shanley T, Blazar B, Larson R, FitzGerald G, Reis S, Pearson T, Buchanan T, McPherson D, Brasier A, Toto R, Disis M, Drezner M, Bernard G, Clore J, Evanoff B, Imperato-McGinley J, Sherwin R, Pulley J. CTSA Principal Investigators, et al. Among authors: tobacman l. Clin Transl Sci. 2012 Apr;5(2):121-9. doi: 10.1111/j.1752-8062.2012.00401.x. Epub 2012 Mar 27. Clin Transl Sci. 2012. PMID: 22507116 Free PMC article.
73 results