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Up-regulation of FXR isoforms is not required for stimulation of the expression of genes involved in the lack of response of colon cancer to chemotherapy.
Martinez-Becerra P, Monte I, Romero MR, Serrano MA, Vaquero J, Macias RI, Del Rio A, Grañé-Boladeras N, Jimenez F, San-Martin FG, Pastor-Anglada M, Marin JJ. Martinez-Becerra P, et al. Pharmacol Res. 2012 Nov;66(5):419-27. doi: 10.1016/j.phrs.2012.07.005. Epub 2012 Aug 8. Pharmacol Res. 2012. PMID: 22898327
Inhibition of Na+-taurocholate Co-transporting polypeptide-mediated bile acid transport by cholestatic sulfated progesterone metabolites.
Abu-Hayyeh S, Martinez-Becerra P, Sheikh Abdul Kadir SH, Selden C, Romero MR, Rees M, Marschall HU, Marin JJ, Williamson C. Abu-Hayyeh S, et al. Among authors: martinez becerra p. J Biol Chem. 2010 May 28;285(22):16504-12. doi: 10.1074/jbc.M109.072140. Epub 2010 Feb 20. J Biol Chem. 2010. PMID: 20177056 Free PMC article.