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IKKbeta/NF-kappaB activation causes severe muscle wasting in mice.
Cai D, Frantz JD, Tawa NE Jr, Melendez PA, Oh BC, Lidov HG, Hasselgren PO, Frontera WR, Lee J, Glass DJ, Shoelson SE. Cai D, et al. Among authors: shoelson se. Cell. 2004 Oct 15;119(2):285-98. doi: 10.1016/j.cell.2004.09.027. Cell. 2004. PMID: 15479644 Free article.
Regulation of IkappaB kinase and NF-kappaB in contracting adult rat skeletal muscle.
Ho RC, Hirshman MF, Li Y, Cai D, Farmer JR, Aschenbach WG, Witczak CA, Shoelson SE, Goodyear LJ. Ho RC, et al. Among authors: shoelson se. Am J Physiol Cell Physiol. 2005 Oct;289(4):C794-801. doi: 10.1152/ajpcell.00632.2004. Epub 2005 May 11. Am J Physiol Cell Physiol. 2005. PMID: 15888549 Free article.
Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE*3-Leiden mice.
Wong MC, van Diepen JA, Hu L, Guigas B, de Boer HC, van Puijvelde GH, Kuiper J, van Zonneveld AJ, Shoelson SE, Voshol PJ, Romijn JA, Havekes LM, Tamsma JT, Rensen PC, Hiemstra PS, Berbée JF. Wong MC, et al. Among authors: shoelson se. Atherosclerosis. 2012 Feb;220(2):362-8. doi: 10.1016/j.atherosclerosis.2011.06.055. Epub 2011 Jul 12. Atherosclerosis. 2012. PMID: 21798539 Free PMC article.
Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health.
Zhang N, Valentine JM, Zhou Y, Li ME, Zhang Y, Bhattacharya A, Walsh ME, Fischer KE, Austad SN, Osmulski P, Gaczynska M, Shoelson SE, Van Remmen H, Chen HI, Chen Y, Liang H, Musi N. Zhang N, et al. Among authors: shoelson se. Aging Cell. 2017 Aug;16(4):847-858. doi: 10.1111/acel.12613. Epub 2017 May 29. Aging Cell. 2017. PMID: 28556540 Free PMC article.
192 results