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Page 1
Evidence of oncogene-induced senescence in thyroid carcinogenesis.
Vizioli MG, Possik PA, Tarantino E, Meissl K, Borrello MG, Miranda C, Anania MC, Pagliardini S, Seregni E, Pierotti MA, Pilotti S, Peeper DS, Greco A. Vizioli MG, et al. Among authors: possik pa. Endocr Relat Cancer. 2011 Dec 1;18(6):743-57. doi: 10.1530/ERC-11-0240. Print 2011 Dec. Endocr Relat Cancer. 2011. PMID: 21937739
Parallel in vivo and in vitro melanoma RNAi dropout screens reveal synthetic lethality between hypoxia and DNA damage response inhibition.
Possik PA, Müller J, Gerlach C, Kenski JC, Huang X, Shahrabi A, Krijgsman O, Song JY, Smit MA, Gerritsen B, Lieftink C, Kemper K, Michaut M, Beijersbergen RL, Wessels L, Schumacher TN, Peeper DS. Possik PA, et al. Cell Rep. 2014 Nov 20;9(4):1375-86. doi: 10.1016/j.celrep.2014.10.024. Epub 2014 Nov 6. Cell Rep. 2014. PMID: 25456132 Free article.
ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma.
Smit MA, Maddalo G, Greig K, Raaijmakers LM, Possik PA, van Breukelen B, Cappadona S, Heck AJ, Altelaar AF, Peeper DS. Smit MA, et al. Among authors: possik pa. Mol Syst Biol. 2014 Dec 23;10(12):772. doi: 10.15252/msb.20145450. Mol Syst Biol. 2014. PMID: 25538140 Free PMC article.
Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK.
Vogel CJ, Smit MA, Maddalo G, Possik PA, Sparidans RW, van der Burg SH, Verdegaal EM, Heck AJ, Samatar AA, Beijnen JH, Altelaar AF, Peeper DS. Vogel CJ, et al. Among authors: possik pa. Pigment Cell Melanoma Res. 2015 May;28(3):307-17. doi: 10.1111/pcmr.12364. Epub 2015 Apr 6. Pigment Cell Melanoma Res. 2015. PMID: 25728708
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.
Müller J, Krijgsman O, Tsoi J, Robert L, Hugo W, Song C, Kong X, Possik PA, Cornelissen-Steijger PD, Geukes Foppen MH, Kemper K, Goding CR, McDermott U, Blank C, Haanen J, Graeber TG, Ribas A, Lo RS, Peeper DS. Müller J, et al. Among authors: possik pa. Nat Commun. 2014 Dec 15;5:5712. doi: 10.1038/ncomms6712. Nat Commun. 2014. PMID: 25502142 Free PMC article.
TOP1 modulation during melanoma progression and in adaptative resistance to BRAF and MEK inhibitors.
Oliveira ÉA, Chauhan J, Silva JRD, Carvalho LADC, Dias D, Carvalho DG, Watanabe LRM, Rebecca VW, Mills G, Lu Y, da Silva ASF, Consolaro MEL, Herlyn M, Possik PA, Goding CR, Maria-Engler SS. Oliveira ÉA, et al. Among authors: possik pa. Pharmacol Res. 2021 Nov;173:105911. doi: 10.1016/j.phrs.2021.105911. Epub 2021 Sep 22. Pharmacol Res. 2021. PMID: 34560251 Free PMC article.
22 results