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Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis.
Genes Dev. 2012 May 15;26(10):1055-69. doi: 10.1101/gad.187252.112. Epub 2012 May 1.
Genes Dev. 2012.
PMID: 22549727
Free PMC article.
BRAF(E600) in benign and malignant human tumours.
Michaloglou C, Vredeveld LC, Mooi WJ, Peeper DS.
Michaloglou C, et al. Among authors: vredeveld lc.
Oncogene. 2008 Feb 7;27(7):877-95. doi: 10.1038/sj.onc.1210704. Epub 2007 Aug 27.
Oncogene. 2008.
PMID: 17724477
Review.
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BRAFE600-associated senescence-like cell cycle arrest of human naevi.
Michaloglou C, Vredeveld LC, Soengas MS, Denoyelle C, Kuilman T, van der Horst CM, Majoor DM, Shay JW, Mooi WJ, Peeper DS.
Michaloglou C, et al. Among authors: vredeveld lc.
Nature. 2005 Aug 4;436(7051):720-4. doi: 10.1038/nature03890.
Nature. 2005.
PMID: 16079850
Free article.
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Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.
Kuilman T, Michaloglou C, Vredeveld LC, Douma S, van Doorn R, Desmet CJ, Aarden LA, Mooi WJ, Peeper DS.
Kuilman T, et al. Among authors: vredeveld lc.
Cell. 2008 Jun 13;133(6):1019-31. doi: 10.1016/j.cell.2008.03.039.
Cell. 2008.
PMID: 18555778
Free article.
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Functional identification of LRF as an oncogene that bypasses RASV12-induced senescence via upregulation of CYCLIN E.
Vredeveld LC, Rowland BD, Douma S, Bernards R, Peeper DS.
Vredeveld LC, et al.
Carcinogenesis. 2010 Feb;31(2):201-7. doi: 10.1093/carcin/bgp296. Epub 2009 Nov 25.
Carcinogenesis. 2010.
PMID: 19942610
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The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor.
Schlisio S, Kenchappa RS, Vredeveld LC, George RE, Stewart R, Greulich H, Shahriari K, Nguyen NV, Pigny P, Dahia PL, Pomeroy SL, Maris JM, Look AT, Meyerson M, Peeper DS, Carter BD, Kaelin WG Jr.
Schlisio S, et al. Among authors: vredeveld lc.
Genes Dev. 2008 Apr 1;22(7):884-93. doi: 10.1101/gad.1648608. Epub 2008 Mar 11.
Genes Dev. 2008.
PMID: 18334619
Free PMC article.
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PR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticle.
Creyghton MP, Roël G, Eichhorn PJ, Vredeveld LC, Destrée O, Bernards R.
Creyghton MP, et al. Among authors: vredeveld lc.
Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5397-402. doi: 10.1073/pnas.0507237103. Epub 2006 Mar 27.
Proc Natl Acad Sci U S A. 2006.
PMID: 16567647
Free PMC article.
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