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Melanesian blond hair is caused by an amino acid change in TYRP1.
Kenny EE, Timpson NJ, Sikora M, Yee MC, Moreno-Estrada A, Eng C, Huntsman S, Burchard EG, Stoneking M, Bustamante CD, Myles S. Kenny EE, et al. Among authors: eng c. Science. 2012 May 4;336(6081):554. doi: 10.1126/science.1217849. Science. 2012. PMID: 22556244 Free PMC article.
Beta 2-adrenergic receptor polymorphisms: pharmacogenetic response to bronchodilator among African American asthmatics.
Tsai HJ, Shaikh N, Kho JY, Battle N, Naqvi M, Navarro D, Matallana H, Lilly CM, Eng CS, Kumar G, Thyne S, Watson HG, Meade K, LeNoir M, Choudhry S, Burchard EG; Study of African Americans, Asthma, Genes Environments (SAGE). Tsai HJ, et al. Hum Genet. 2006 Jun;119(5):547-57. doi: 10.1007/s00439-006-0169-2. Epub 2006 Apr 5. Hum Genet. 2006. PMID: 16596417
ORMDL3 gene is associated with asthma in three ethnically diverse populations.
Galanter J, Choudhry S, Eng C, Nazario S, Rodríguez-Santana JR, Casal J, Torres-Palacios A, Salas J, Chapela R, Watson HG, Meade K, LeNoir M, Rodríguez-Cintrón W, Avila PC, Burchard EG. Galanter J, et al. Among authors: eng c. Am J Respir Crit Care Med. 2008 Jun 1;177(11):1194-200. doi: 10.1164/rccm.200711-1644OC. Epub 2008 Feb 28. Am J Respir Crit Care Med. 2008. PMID: 18310477 Free PMC article.
An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity.
Seibold MA, Wang B, Eng C, Kumar G, Beckman KB, Sen S, Choudhry S, Meade K, Lenoir M, Watson HG, Thyne S, Williams LK, Kumar R, Weiss KB, Grammer LC, Avila PC, Schleimer RP, Burchard EG, Brenner R. Seibold MA, et al. Among authors: eng c. Hum Mol Genet. 2008 Sep 1;17(17):2681-90. doi: 10.1093/hmg/ddn168. Epub 2008 Jun 4. Hum Mol Genet. 2008. PMID: 18535015 Free PMC article.
Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations.
Galanter JM, Torgerson D, Gignoux CR, Sen S, Roth LA, Via M, Aldrich MC, Eng C, Huntsman S, Rodriguez-Santana J, Rodriguez-Cintrón W, Chapela R, Ford JG, Burchard EG. Galanter JM, et al. Among authors: eng c. J Allergy Clin Immunol. 2011 Jul;128(1):37-43.e12. doi: 10.1016/j.jaci.2011.03.050. Epub 2011 May 28. J Allergy Clin Immunol. 2011. PMID: 21621256 Free PMC article.
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
Torgerson DG, Ampleford EJ, Chiu GY, Gauderman WJ, Gignoux CR, Graves PE, Himes BE, Levin AM, Mathias RA, Hancock DB, Baurley JW, Eng C, Stern DA, Celedón JC, Rafaels N, Capurso D, Conti DV, Roth LA, Soto-Quiros M, Togias A, Li X, Myers RA, Romieu I, Van Den Berg DJ, Hu D, Hansel NN, Hernandez RD, Israel E, Salam MT, Galanter J, Avila PC, Avila L, Rodriquez-Santana JR, Chapela R, Rodriguez-Cintron W, Diette GB, Adkinson NF, Abel RA, Ross KD, Shi M, Faruque MU, Dunston GM, Watson HR, Mantese VJ, Ezurum SC, Liang L, Ruczinski I, Ford JG, Huntsman S, Chung KF, Vora H, Li X, Calhoun WJ, Castro M, Sienra-Monge JJ, del Rio-Navarro B, Deichmann KA, Heinzmann A, Wenzel SE, Busse WW, Gern JE, Lemanske RF Jr, Beaty TH, Bleecker ER, Raby BA, Meyers DA, London SJ; Mexico City Childhood Asthma Study (MCAAS); Gilliland FD; Children's Health Study (CHS) and HARBORS study; Burchard EG; Genetics of Asthma in Latino Americans (GALA) Study, Study of Genes-Environment and Admixture in Latino Americans (GALA2) and Study of African Americans, Asthma, Genes & Environments (SAGE); Martinez FD; Childhood Asthma Research and Education (CARE) Network; Weiss ST; Childhood Asthma Management Program… See abstract for full author list ➔ Torgerson DG, et al. Among authors: eng c. Nat Genet. 2011 Jul 31;43(9):887-92. doi: 10.1038/ng.888. Nat Genet. 2011. PMID: 21804549 Free PMC article.
Furthering the link between the sarcomere and primary cardiomyopathies: restrictive cardiomyopathy associated with multiple mutations in genes previously associated with hypertrophic or dilated cardiomyopathy.
Caleshu C, Sakhuja R, Nussbaum RL, Schiller NB, Ursell PC, Eng C, De Marco T, McGlothlin D, Burchard EG, Rame JE. Caleshu C, et al. Among authors: eng c. Am J Med Genet A. 2011 Sep;155A(9):2229-35. doi: 10.1002/ajmg.a.34097. Epub 2011 Aug 5. Am J Med Genet A. 2011. PMID: 21823217 Free PMC article.
Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas.
Fejerman L, Chen GK, Eng C, Huntsman S, Hu D, Williams A, Pasaniuc B, John EM, Via M, Gignoux C, Ingles S, Monroe KR, Kolonel LN, Torres-Mejía G, Pérez-Stable EJ, Burchard EG, Henderson BE, Haiman CA, Ziv E. Fejerman L, et al. Among authors: eng c. Hum Mol Genet. 2012 Apr 15;21(8):1907-17. doi: 10.1093/hmg/ddr617. Epub 2012 Jan 6. Hum Mol Genet. 2012. PMID: 22228098 Free PMC article.
1,864 results