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Cytotoxicity of superoxide dismutase 1 in cultured cells is linked to Zn2+ chelation.
PLoS One. 2012;7(4):e36104. doi: 10.1371/journal.pone.0036104. Epub 2012 Apr 25.
PLoS One. 2012.
PMID: 22558346
Free PMC article.
Folding catalysis by transient coordination of Zn2+ to the Cu ligands of the ALS-associated enzyme Cu/Zn superoxide dismutase 1.
Leinartaite L, Saraboji K, Nordlund A, Logan DT, Oliveberg M.
Leinartaite L, et al.
J Am Chem Soc. 2010 Sep 29;132(38):13495-504. doi: 10.1021/ja1057136.
J Am Chem Soc. 2010.
PMID: 20822138
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Global structural motions from the strain of a single hydrogen bond.
Danielsson J, Awad W, Saraboji K, Kurnik M, Lang L, Leinartaite L, Marklund SL, Logan DT, Oliveberg M.
Danielsson J, et al. Among authors: leinartaite l.
Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3829-34. doi: 10.1073/pnas.1217306110. Epub 2013 Feb 19.
Proc Natl Acad Sci U S A. 2013.
PMID: 23431167
Free PMC article.
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Disulfide scrambling in superoxide dismutase 1 reduces its cytotoxic effect in cultured cells and promotes protein aggregation.
Leinartaitė L, Johansson AS.
Leinartaitė L, et al.
PLoS One. 2013 Oct 15;8(10):e78060. doi: 10.1371/journal.pone.0078060. eCollection 2013.
PLoS One. 2013.
PMID: 24143259
Free PMC article.
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Functional features cause misfolding of the ALS-provoking enzyme SOD1.
Nordlund A, Leinartaite L, Saraboji K, Aisenbrey C, Gröbner G, Zetterström P, Danielsson J, Logan DT, Oliveberg M.
Nordlund A, et al. Among authors: leinartaite l.
Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9667-72. doi: 10.1073/pnas.0812046106. Epub 2009 Jun 2.
Proc Natl Acad Sci U S A. 2009.
PMID: 19497878
Free PMC article.
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Folding Underlies Bidirectional Role of GPR37/Pael-R in Parkinson Disease.
Leinartaité L, Svenningsson P.
Leinartaité L, et al.
Trends Pharmacol Sci. 2017 Aug;38(8):749-760. doi: 10.1016/j.tips.2017.05.006. Epub 2017 Jun 16.
Trends Pharmacol Sci. 2017.
PMID: 28629580
Review.
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Overexpression of α-synuclein simultaneously increases glutamate NMDA receptor phosphorylation and reduces glucocerebrosidase activity.
Yang J, Hertz E, Zhang X, Leinartaité L, Lundius EG, Li J, Svenningsson P.
Yang J, et al. Among authors: leinartaite l.
Neurosci Lett. 2016 Jan 12;611:51-8. doi: 10.1016/j.neulet.2015.11.023. Epub 2015 Dec 2.
Neurosci Lett. 2016.
PMID: 26610904
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