Holloway JW - Search Results

1

Genome-wide association study to identify genetic determinants of severe asthma.

Wan YI, Shrine NR, Soler Artigas M, Wain LV, Blakey JD, Moffatt MF, Bush A, Chung KF, Cookson WO, Strachan DP, Heaney L, Al-Momani BA, Mansur AH, Manney S, Thomson NC, Chaudhuri R, Brightling CE, Bafadhel M, Singapuri A, Niven R, Simpson A, Holloway JW, Howarth PH, Hui J, Musk AW, James AL; Australian Asthma Genetics Consortium; Brown MA, Baltic S, Ferreira MA, Thompson PJ, Tobin MD, Sayers I, Hall IP. Wan YI, et al. Among authors: holloway jw. Thorax. 2012 Sep;67(9):762-8. doi: 10.1136/thoraxjnl-2011-201262. Epub 2012 May 5. Thorax. 2012. PMID: 22561531 Free article.

2

Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast.

Sampson AP, Siddiqui S, Buchanan D, Howarth PH, Holgate ST, Holloway JW, Sayers I. Sampson AP, et al. Among authors: holloway jw. Thorax. 2000 Oct;55 Suppl 2(Suppl 2):S28-31. doi: 10.1136/thorax.55.suppl_2.s28. Thorax. 2000. PMID: 10992553 Free PMC article. No abstract available.

3

A first trial of retrospective collaboration for positional cloning in complex inheritance: assay of the cytokine region on chromosome 5 by the consortium on asthma genetics (COAG).

Lonjou C, Barnes K, Chen H, Cookson WO, Deichmann KA, Hall IP, Holloway JW, Laitinen T, Palmer LJ, Wjst M, Morton NE. Lonjou C, et al. Among authors: holloway jw. Proc Natl Acad Sci U S A. 2000 Sep 26;97(20):10942-7. doi: 10.1073/pnas.97.20.10942. Proc Natl Acad Sci U S A. 2000. PMID: 11005866 Free PMC article. Clinical Trial.

4

Linkage analysis of the 5q31-33 candidate region for asthma in 240 UK families.

Holloway JW, Lonjou C, Beghé B, Peng Q, Gaunt TR, Gomes I, Hall IP, Dewar JC, Wilkinson J, Thomas NS, Holgate ST, Morton NE. Holloway JW, et al. Genes Immun. 2001 Feb;2(1):20-4. doi: 10.1038/sj.gene.6363723. Genes Immun. 2001. PMID: 11294563

5

Invited lecture: activation of the epithelial mesenchymal trophic unit in the pathogenesis of asthma.

Holgate ST, Lackie PM, Howarth PH, Roche WR, Puddicombe SM, Richter A, Wilson SJ, Holloway JW, Davies DE. Holgate ST, et al. Among authors: holloway jw. Int Arch Allergy Immunol. 2001 Jan-Mar;124(1-3):253-8. doi: 10.1159/000053726. Int Arch Allergy Immunol. 2001. PMID: 11306984

6

Single region linkage analyses of asthma: description of data sets.

Palmer LJ, Cookson WO, Deichmann KA, Holloway JW, Laitinen T. Palmer LJ, et al. Among authors: holloway jw. Genet Epidemiol. 2001;21 Suppl 1:S9-15. doi: 10.1002/gepi.2001.21.s1.s9. Genet Epidemiol. 2001. PMID: 11793793

7

Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthma.

Sayers I, Barton S, Rorke S, Beghé B, Hayward B, Van Eerdewegh P, Keith T, Clough JB, Ye S, Holloway JW, Sampson AP, Holgate ST. Sayers I, et al. Among authors: holloway jw. Thorax. 2003 May;58(5):417-24. doi: 10.1136/thorax.58.5.417. Thorax. 2003. PMID: 12728163 Free PMC article.

8

Promoter polymorphism in the 5-lipoxygenase (ALOX5) and 5-lipoxygenase-activating protein (ALOX5AP) genes and asthma susceptibility in a Caucasian population.

Sayers I, Barton S, Rorke S, Sawyer J, Peng Q, Beghé B, Ye S, Keith T, Clough JB, Holloway JW, Sampson AP, Holgate ST. Sayers I, et al. Among authors: holloway jw. Clin Exp Allergy. 2003 Aug;33(8):1103-10. doi: 10.1046/j.1365-2222.2003.01733.x. Clin Exp Allergy. 2003. PMID: 12911785

9

Polymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a Caucasian population.

Beghé B, Barton S, Rorke S, Peng Q, Sayers I, Gaunt T, Keith TP, Clough JB, Holgate ST, Holloway JW. Beghé B, et al. Among authors: holloway jw. Clin Exp Allergy. 2003 Aug;33(8):1111-7. doi: 10.1046/j.1365-2222.2003.01731.x. Clin Exp Allergy. 2003. PMID: 12911786

10

Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities.

Holgate ST, Holloway J, Wilson S, Howarth PH, Haitchi HM, Babu S, Davies DE. Holgate ST, et al. J Allergy Clin Immunol. 2006 Mar;117(3):496-506; quiz 507. doi: 10.1016/j.jaci.2006.01.039. J Allergy Clin Immunol. 2006. PMID: 16522446 Review.

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