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Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages.
Hoeffel G, Wang Y, Greter M, See P, Teo P, Malleret B, Leboeuf M, Low D, Oller G, Almeida F, Choy SH, Grisotto M, Renia L, Conway SJ, Stanley ER, Chan JK, Ng LG, Samokhvalov IM, Merad M, Ginhoux F. Hoeffel G, et al. Among authors: leboeuf m. J Exp Med. 2012 Jun 4;209(6):1167-81. doi: 10.1084/jem.20120340. Epub 2012 May 7. J Exp Med. 2012. PMID: 22565823 Free PMC article.
Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state.
Ginhoux F, Collin MP, Bogunovic M, Abel M, Leboeuf M, Helft J, Ochando J, Kissenpfennig A, Malissen B, Grisotto M, Snoeck H, Randolph G, Merad M. Ginhoux F, et al. Among authors: leboeuf m. J Exp Med. 2007 Dec 24;204(13):3133-46. doi: 10.1084/jem.20071733. Epub 2007 Dec 17. J Exp Med. 2007. PMID: 18086862 Free PMC article.
Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation.
Hashimoto D, Chow A, Greter M, Saenger Y, Kwan WH, Leboeuf M, Ginhoux F, Ochando JC, Kunisaki Y, van Rooijen N, Liu C, Teshima T, Heeger PS, Stanley ER, Frenette PS, Merad M. Hashimoto D, et al. Among authors: leboeuf m. J Exp Med. 2011 May 9;208(5):1069-82. doi: 10.1084/jem.20101709. Epub 2011 May 2. J Exp Med. 2011. PMID: 21536742 Free PMC article.
Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes.
Hashimoto D, Chow A, Noizat C, Teo P, Beasley MB, Leboeuf M, Becker CD, See P, Price J, Lucas D, Greter M, Mortha A, Boyer SW, Forsberg EC, Tanaka M, van Rooijen N, García-Sastre A, Stanley ER, Ginhoux F, Frenette PS, Merad M. Hashimoto D, et al. Among authors: leboeuf m. Immunity. 2013 Apr 18;38(4):792-804. doi: 10.1016/j.immuni.2013.04.004. Immunity. 2013. PMID: 23601688 Free PMC article.
BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.
Berres ML, Lim KP, Peters T, Price J, Takizawa H, Salmon H, Idoyaga J, Ruzo A, Lupo PJ, Hicks MJ, Shih A, Simko SJ, Abhyankar H, Chakraborty R, Leboeuf M, Beltrão M, Lira SA, Heym KM, Bigley V, Collin M, Manz MG, McClain K, Merad M, Allen CE. Berres ML, et al. Among authors: leboeuf m. J Exp Med. 2014 Apr 7;211(4):669-83. doi: 10.1084/jem.20130977. Epub 2014 Mar 17. J Exp Med. 2014. PMID: 24638167 Free PMC article.
Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche.
Chow A, Lucas D, Hidalgo A, Méndez-Ferrer S, Hashimoto D, Scheiermann C, Battista M, Leboeuf M, Prophete C, van Rooijen N, Tanaka M, Merad M, Frenette PS. Chow A, et al. Among authors: leboeuf m. J Exp Med. 2011 Feb 14;208(2):261-71. doi: 10.1084/jem.20101688. Epub 2011 Jan 31. J Exp Med. 2011. PMID: 21282381 Free PMC article.
Origin of the lamina propria dendritic cell network.
Bogunovic M, Ginhoux F, Helft J, Shang L, Hashimoto D, Greter M, Liu K, Jakubzick C, Ingersoll MA, Leboeuf M, Stanley ER, Nussenzweig M, Lira SA, Randolph GJ, Merad M. Bogunovic M, et al. Among authors: leboeuf m. Immunity. 2009 Sep 18;31(3):513-25. doi: 10.1016/j.immuni.2009.08.010. Epub 2009 Sep 10. Immunity. 2009. PMID: 19733489 Free PMC article.
RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions.
Hogstad B, Berres ML, Chakraborty R, Tang J, Bigenwald C, Serasinghe M, Lim KPH, Lin H, Man TK, Remark R, Baxter S, Kana V, Jordan S, Karoulia Z, Kwan WH, Leboeuf M, Brandt E, Salmon H, McClain K, Poulikakos P, Chipuk J, Mulder WJM, Allen CE, Merad M. Hogstad B, et al. Among authors: leboeuf m. J Exp Med. 2018 Jan 2;215(1):319-336. doi: 10.1084/jem.20161881. Epub 2017 Dec 20. J Exp Med. 2018. PMID: 29263218 Free PMC article.
132 results