Qureshi S - Search Results

1

A genome-wide siRNA screen to identify modulators of insulin sensitivity and gluconeogenesis.

Yang R, Lacson RG, Castriota G, Zhang XD, Liu Y, Zhao W, Einstein M, Camargo LM, Qureshi S, Wong KK, Zhang BB, Ferrer M, Berger JP. Yang R, et al. Among authors: qureshi s. PLoS One. 2012;7(5):e36384. doi: 10.1371/journal.pone.0036384. Epub 2012 May 9. PLoS One. 2012. PMID: 22590537 Free PMC article.

2

RNAi-mediated germline knockdown of FABP4 increases body weight but does not improve the deranged nutrient metabolism of diet-induced obese mice.

Yang R, Castriota G, Chen Y, Cleary MA, Ellsworth K, Shin MK, Tran JL, Vogt TF, Wu M, Xu S, Yang X, Zhang BB, Berger JP, Qureshi SA. Yang R, et al. Among authors: qureshi sa. Int J Obes (Lond). 2011 Feb;35(2):217-25. doi: 10.1038/ijo.2010.128. Epub 2010 Jul 6. Int J Obes (Lond). 2011. PMID: 20603627 Free PMC article.

3

Cloning and expression of canine glucagon receptor and its use to evaluate glucagon receptor antagonists in vitro and in vivo.

Yang X, Yates ML, Candelore MR, Feeney W, Hora D, Kim RM, Parmee ER, Berger JP, Zhang BB, Qureshi SA. Yang X, et al. Eur J Pharmacol. 2007 Jan 19;555(1):8-16. doi: 10.1016/j.ejphar.2006.10.033. Epub 2006 Oct 21. Eur J Pharmacol. 2007. PMID: 17140563

4

Anti-diabetic efficacy and impact on amino acid metabolism of GRA1, a novel small-molecule glucagon receptor antagonist.

Mu J, Qureshi SA, Brady EJ, Muise ES, Candelore MR, Jiang G, Li Z, Wu MS, Yang X, Dallas-Yang Q, Miller C, Xiong Y, Langdon RB, Parmee ER, Zhang BB. Mu J, et al. Among authors: qureshi sa. PLoS One. 2012;7(11):e49572. doi: 10.1371/journal.pone.0049572. Epub 2012 Nov 19. PLoS One. 2012. PMID: 23185367 Free PMC article.

5

Detection of glucagon-dependent GTPgammaS binding in high-throughput format.

Dallas-Yang Q, Qureshi SA, Xie D, Zhang BB, Jiang G. Dallas-Yang Q, et al. Anal Biochem. 2002 Feb 1;301(1):156-9. doi: 10.1006/abio.2001.5483. Anal Biochem. 2002. PMID: 11811981 No abstract available.

6

Regulation of insulin signal transduction pathway by a small-molecule insulin receptor activator.

Ding VD, Qureshi SA, Szalkowski D, Li Z, Biazzo-Ashnault DE, Xie D, Liu K, Jones AB, Moller DE, Zhang BB. Ding VD, et al. Biochem J. 2002 Oct 1;367(Pt 1):301-6. doi: 10.1042/BJ20020708. Biochem J. 2002. PMID: 12036431 Free PMC article.

7

Hepatic glucagon receptor binding and glucose-lowering in vivo by peptidyl and non-peptidyl glucagon receptor antagonists.

Dallas-Yang Q, Shen X, Strowski M, Brady E, Saperstein R, Gibson RE, Szalkowski D, Qureshi SA, Candelore MR, Fenyk-Melody JE, Parmee ER, Zhang BB, Jiang G. Dallas-Yang Q, et al. Eur J Pharmacol. 2004 Oct 6;501(1-3):225-34. doi: 10.1016/j.ejphar.2004.08.023. Eur J Pharmacol. 2004. PMID: 15464082

8

Discovery of potent, orally active benzimidazole glucagon receptor antagonists.

Kim RM, Chang J, Lins AR, Brady E, Candelore MR, Dallas-Yang Q, Ding V, Dragovic J, Iliff S, Jiang G, Mock S, Qureshi S, Saperstein R, Szalkowski D, Tamvakopoulos C, Tota L, Wright M, Yang X, Tata JR, Chapman K, Zhang BB, Parmee ER. Kim RM, et al. Among authors: qureshi s. Bioorg Med Chem Lett. 2008 Jul 1;18(13):3701-5. doi: 10.1016/j.bmcl.2008.05.072. Epub 2008 May 22. Bioorg Med Chem Lett. 2008. PMID: 18539028

9

Discovery of a novel glucagon receptor antagonist N-[(4-{(1S)-1-[3-(3, 5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl]ethyl}phenyl)carbonyl]-β-alanine (MK-0893) for the treatment of type II diabetes.

Xiong Y, Guo J, Candelore MR, Liang R, Miller C, Dallas-Yang Q, Jiang G, McCann PE, Qureshi SA, Tong X, Xu SS, Shang J, Vincent SH, Tota LM, Wright MJ, Yang X, Zhang BB, Tata JR, Parmee ER. Xiong Y, et al. J Med Chem. 2012 Jul 12;55(13):6137-48. doi: 10.1021/jm300579z. Epub 2012 Jun 28. J Med Chem. 2012. PMID: 22708876

10

Detection of insulin receptor tyrosine kinase activity using time-resolved fluorescence energy transfer technology.

Biazzo-Ashnault DE, Park YW, Cummings RT, Ding V, Moller DE, Zhang BB, Qureshi SA. Biazzo-Ashnault DE, et al. Among authors: qureshi sa. Anal Biochem. 2001 Apr 1;291(1):155-8. doi: 10.1006/abio.2001.5027. Anal Biochem. 2001. PMID: 11262169 No abstract available.

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