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CD25 blockade depletes and selectively reprograms regulatory T cells in concert with immunotherapy in cancer patients.
Rech AJ, Mick R, Martin S, Recio A, Aqui NA, Powell DJ Jr, Colligon TA, Trosko JA, Leinbach LI, Pletcher CH, Tweed CK, DeMichele A, Fox KR, Domchek SM, Riley JL, Vonderheide RH. Rech AJ, et al. Sci Transl Med. 2012 May 16;4(134):134ra62. doi: 10.1126/scitranslmed.3003330. Sci Transl Med. 2012. PMID: 22593175 Free PMC article. Clinical Trial.
Collapse of the CD27+ B-cell compartment associated with systemic plasmacytosis in patients with advanced melanoma and other cancers.
Carpenter EL, Mick R, Rech AJ, Beatty GL, Colligon TA, Rosenfeld MR, Kaplan DE, Chang KM, Domchek SM, Kanetsky PA, Fecher LA, Flaherty KT, Schuchter LM, Vonderheide RH. Carpenter EL, et al. Among authors: rech aj. Clin Cancer Res. 2009 Jul 1;15(13):4277-87. doi: 10.1158/1078-0432.CCR-09-0537. Epub 2009 Jun 23. Clin Cancer Res. 2009. PMID: 19549767 Free PMC article.
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer.
Twyman-Saint Victor C, Rech AJ, Maity A, Rengan R, Pauken KE, Stelekati E, Benci JL, Xu B, Dada H, Odorizzi PM, Herati RS, Mansfield KD, Patsch D, Amaravadi RK, Schuchter LM, Ishwaran H, Mick R, Pryma DA, Xu X, Feldman MD, Gangadhar TC, Hahn SM, Wherry EJ, Vonderheide RH, Minn AJ. Twyman-Saint Victor C, et al. Among authors: rech aj. Nature. 2015 Apr 16;520(7547):373-7. doi: 10.1038/nature14292. Epub 2015 Mar 9. Nature. 2015. PMID: 25754329 Free PMC article.
Lack of immunoediting in murine pancreatic cancer reversed with neoantigen.
Evans RA, Diamond MS, Rech AJ, Chao T, Richardson MW, Lin JH, Bajor DL, Byrne KT, Stanger BZ, Riley JL, Markosyan N, Winograd R, Vonderheide RH. Evans RA, et al. Among authors: rech aj. JCI Insight. 2016 Sep 8;1(14):e88328. doi: 10.1172/jci.insight.88328. JCI Insight. 2016. PMID: 27642636 Free PMC article.
T-Cell Transfer Therapy Targeting Mutant KRAS.
Rech AJ, Vonderheide RH. Rech AJ, et al. N Engl J Med. 2017 Feb 16;376(7):e11. doi: 10.1056/NEJMc1616637. N Engl J Med. 2017. PMID: 28207208 No abstract available.
24 results