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Large-scale mapping and mutagenesis of human transcriptional effector domains.
DelRosso N, Tycko J, Suzuki P, Andrews C, Aradhana, Mukund A, Liongson I, Ludwig C, Spees K, Fordyce P, Bassik MC, Bintu L. DelRosso N, et al. Among authors: bintu l. Nature. 2023 Apr;616(7956):365-372. doi: 10.1038/s41586-023-05906-y. Epub 2023 Apr 5. Nature. 2023. PMID: 37020022 Free PMC article.
The sound of silence: Transgene silencing in mammalian cell engineering.
Cabrera A, Edelstein HI, Glykofrydis F, Love KS, Palacios S, Tycko J, Zhang M, Lensch S, Shields CE, Livingston M, Weiss R, Zhao H, Haynes KA, Morsut L, Chen YY, Khalil AS, Wong WW, Collins JJ, Rosser SJ, Polizzi K, Elowitz MB, Fussenegger M, Hilton IB, Leonard JN, Bintu L, Galloway KE, Deans TL. Cabrera A, et al. Among authors: bintu l. Cell Syst. 2022 Dec 21;13(12):950-973. doi: 10.1016/j.cels.2022.11.005. Cell Syst. 2022. PMID: 36549273 Free PMC article. Review.
Transcriptional regulation by the numbers: models.
Bintu L, Buchler NE, Garcia HG, Gerland U, Hwa T, Kondev J, Phillips R. Bintu L, et al. Curr Opin Genet Dev. 2005 Apr;15(2):116-24. doi: 10.1016/j.gde.2005.02.007. Curr Opin Genet Dev. 2005. PMID: 15797194 Free PMC article. Review.
Dynamics of epigenetic regulation at the single-cell level.
Bintu L, Yong J, Antebi YE, McCue K, Kazuki Y, Uno N, Oshimura M, Elowitz MB. Bintu L, et al. Science. 2016 Feb 12;351(6274):720-4. doi: 10.1126/science.aab2956. Science. 2016. PMID: 26912859 Free PMC article.
High-Throughput Discovery and Characterization of Human Transcriptional Effectors.
Tycko J, DelRosso N, Hess GT, Aradhana, Banerjee A, Mukund A, Van MV, Ego BK, Yao D, Spees K, Suzuki P, Marinov GK, Kundaje A, Bassik MC, Bintu L. Tycko J, et al. Among authors: bintu l. Cell. 2020 Dec 23;183(7):2020-2035.e16. doi: 10.1016/j.cell.2020.11.024. Epub 2020 Dec 15. Cell. 2020. PMID: 33326746 Free PMC article.
27 results