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769 results

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Page 1
Paired tumor and normal whole genome sequencing of metastatic olfactory neuroblastoma.
Weiss GJ, Liang WS, Izatt T, Arora S, Cherni I, Raju RN, Hostetter G, Kurdoglu A, Christoforides A, Sinari S, Baker AS, Metpally R, Tembe WD, Phillips L, Von Hoff DD, Craig DW, Carpten JD. Weiss GJ, et al. Among authors: von hoff dd. PLoS One. 2012;7(5):e37029. doi: 10.1371/journal.pone.0037029. Epub 2012 May 23. PLoS One. 2012. PMID: 22649506 Free PMC article.
A pilot study using next-generation sequencing in advanced cancers: feasibility and challenges.
Weiss GJ, Liang WS, Demeure MJ, Kiefer JA, Hostetter G, Izatt T, Sinari S, Christoforides A, Aldrich J, Kurdoglu A, Phillips L, Benson H, Reiman R, Baker A, Marsh V, Von Hoff DD, Carpten JD, Craig DW. Weiss GJ, et al. Among authors: von hoff dd. PLoS One. 2013 Oct 30;8(10):e76438. doi: 10.1371/journal.pone.0076438. eCollection 2013. PLoS One. 2013. PMID: 24204627 Free PMC article.
Whole genome sequencing reveals potential targets for therapy in patients with refractory KRAS mutated metastatic colorectal cancer.
Shanmugam V, Ramanathan RK, Lavender NA, Sinari S, Chadha M, Liang WS, Kurdoglu A, Izatt T, Christoforides A, Benson H, Phillips L, Baker A, Murray C, Hostetter G, Von Hoff DD, Craig DW, Carpten JD. Shanmugam V, et al. Among authors: von hoff dd. BMC Med Genomics. 2014 Jun 18;7:36. doi: 10.1186/1755-8794-7-36. BMC Med Genomics. 2014. PMID: 24943349 Free PMC article.
Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing.
Liang WS, Craig DW, Carpten J, Borad MJ, Demeure MJ, Weiss GJ, Izatt T, Sinari S, Christoforides A, Aldrich J, Kurdoglu A, Barrett M, Phillips L, Benson H, Tembe W, Braggio E, Kiefer JA, Legendre C, Posner R, Hostetter GH, Baker A, Egan JB, Han H, Lake D, Stites EC, Ramanathan RK, Fonseca R, Stewart AK, Von Hoff D. Liang WS, et al. PLoS One. 2012;7(10):e43192. doi: 10.1371/journal.pone.0043192. Epub 2012 Oct 10. PLoS One. 2012. PMID: 23071490 Free PMC article.
Cancer of the ampulla of Vater: analysis of the whole genome sequence exposes a potential therapeutic vulnerability.
Demeure MJ, Craig DW, Sinari S, Moses TM, Christoforides A, Dinh J, Izatt T, Aldrich J, Decker A, Baker A, Cherni I, Watanabe A, Koep L, Lake D, Hostetter G, Trent JM, Von Hoff DD, Carpten JD. Demeure MJ, et al. Among authors: von hoff dd. Genome Med. 2012 Jul 4;4(7):56. doi: 10.1186/gm357. eCollection 2012. Genome Med. 2012. PMID: 22762308 Free PMC article.
Deep clonal profiling of formalin fixed paraffin embedded clinical samples.
Holley T, Lenkiewicz E, Evers L, Tembe W, Ruiz C, Gsponer JR, Rentsch CA, Bubendorf L, Stapleton M, Amorese D, Legendre C, Cunliffe HE, McCullough AE, Pockaj B, Craig D, Carpten J, Von Hoff D, Iacobuzio-Donahue C, Barrett MT. Holley T, et al. PLoS One. 2012;7(11):e50586. doi: 10.1371/journal.pone.0050586. Epub 2012 Nov 30. PLoS One. 2012. PMID: 23226320 Free PMC article.
Genome and transcriptome sequencing in prospective metastatic triple-negative breast cancer uncovers therapeutic vulnerabilities.
Craig DW, O'Shaughnessy JA, Kiefer JA, Aldrich J, Sinari S, Moses TM, Wong S, Dinh J, Christoforides A, Blum JL, Aitelli CL, Osborne CR, Izatt T, Kurdoglu A, Baker A, Koeman J, Barbacioru C, Sakarya O, De La Vega FM, Siddiqui A, Hoang L, Billings PR, Salhia B, Tolcher AW, Trent JM, Mousses S, Von Hoff D, Carpten JD. Craig DW, et al. Mol Cancer Ther. 2013 Jan;12(1):104-16. doi: 10.1158/1535-7163.MCT-12-0781. Epub 2012 Nov 19. Mol Cancer Ther. 2013. PMID: 23171949
The hedgehog knows many tricks.
Weiss GJ, Mita AC, Von Hoff DD. Weiss GJ, et al. Among authors: von hoff dd. Curr Drug Targets. 2011 Dec;12(14):2091-5. doi: 10.2174/138945011798829429. Curr Drug Targets. 2011. PMID: 21777197 Review.
Hunting the hedgehog pathway.
Weiss GJ, Von Hoff DD. Weiss GJ, et al. Among authors: von hoff dd. Clin Pharmacol Ther. 2010 Jun;87(6):743-7. doi: 10.1038/clpt.2010.34. Epub 2010 Apr 21. Clin Pharmacol Ther. 2010. PMID: 20410878 No abstract available.
Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma.
Borad MJ, Champion MD, Egan JB, Liang WS, Fonseca R, Bryce AH, McCullough AE, Barrett MT, Hunt K, Patel MD, Young SW, Collins JM, Silva AC, Condjella RM, Block M, McWilliams RR, Lazaridis KN, Klee EW, Bible KC, Harris P, Oliver GR, Bhavsar JD, Nair AA, Middha S, Asmann Y, Kocher JP, Schahl K, Kipp BR, Barr Fritcher EG, Baker A, Aldrich J, Kurdoglu A, Izatt T, Christoforides A, Cherni I, Nasser S, Reiman R, Phillips L, McDonald J, Adkins J, Mastrian SD, Placek P, Watanabe AT, Lobello J, Han H, Von Hoff D, Craig DW, Stewart AK, Carpten JD. Borad MJ, et al. PLoS Genet. 2014 Feb 13;10(2):e1004135. doi: 10.1371/journal.pgen.1004135. eCollection 2014 Feb. PLoS Genet. 2014. PMID: 24550739 Free PMC article.
769 results