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Use of protective antigen of Bacillus anthracis as a model recombinant antigen to evaluate toll-like receptors 2, 3, 4, 7 and 9 agonists in mice using established functional antibody assays, antigen-specific antibody assays and cellular assays.
Inglefield J, Catania J, Harris A, Hickey T, Ma Z, Minang J, Baranji K, Spangler T, Look J, Ruiz C, Lu H, Alleva D, Reece JJ, Lacy MJ. Inglefield J, et al. Vaccine. 2022 Sep 9;40(38):5544-5555. doi: 10.1016/j.vaccine.2022.06.017. Epub 2022 Jun 27. Vaccine. 2022. PMID: 35773119