Florez JC - Search Results

1

Impact of common variation in bone-related genes on type 2 diabetes and related traits.

Billings LK, Hsu YH, Ackerman RJ, Dupuis J, Voight BF, Rasmussen-Torvik LJ, Hercberg S, Lathrop M, Barnes D, Langenberg C, Hui J, Fu M, Bouatia-Naji N, Lecoeur C, An P, Magnusson PK, Surakka I, Ripatti S, Christiansen L, Dalgård C, Folkersen L, Grundberg E; MAGIC Investigators; DIAGRAM + Consortium; MuTHER Consortium; ASCOT Investigators; GEFOS Consortium; Eriksson P, Kaprio J, Ohm Kyvik K, Pedersen NL, Borecki IB, Province MA, Balkau B, Froguel P, Shuldiner AR, Palmer LJ, Wareham N, Meneton P, Johnson T, Pankow JS, Karasik D, Meigs JB, Kiel DP, Florez JC. Billings LK, et al. Among authors: florez jc. Diabetes. 2012 Aug;61(8):2176-86. doi: 10.2337/db11-1515. Epub 2012 Jun 14. Diabetes. 2012. PMID: 22698912 Free PMC article.

2

The inherited basis of diabetes mellitus: implications for the genetic analysis of complex traits.

Florez JC, Hirschhorn J, Altshuler D. Florez JC, et al. Annu Rev Genomics Hum Genet. 2003;4:257-91. doi: 10.1146/annurev.genom.4.070802.110436. Annu Rev Genomics Hum Genet. 2003. PMID: 14527304 Review.

3

Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region.

Florez JC, Burtt N, de Bakker PI, Almgren P, Tuomi T, Holmkvist J, Gaudet D, Hudson TJ, Schaffner SF, Daly MJ, Hirschhorn JN, Groop L, Altshuler D. Florez JC, et al. Diabetes. 2004 May;53(5):1360-8. doi: 10.2337/diabetes.53.5.1360. Diabetes. 2004. PMID: 15111507

4

Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes.

Florez JC, Sjögren M, Burtt N, Orho-Melander M, Schayer S, Sun M, Almgren P, Lindblad U, Tuomi T, Gaudet D, Hudson TJ, Daly MJ, Ardlie KG, Hirschhorn JN, Altshuler D, Groop L. Florez JC, et al. Diabetes. 2004 Dec;53(12):3313-8. doi: 10.2337/diabetes.53.12.3313. Diabetes. 2004. PMID: 15561965

5

High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people.

Florez JC, Wiltshire S, Agapakis CM, Burtt NP, de Bakker PI, Almgren P, Bengtsson Boström K, Tuomi T, Gaudet D, Daly MJ, Hirschhorn JN, McCarthy MI, Altshuler D, Groop L. Florez JC, et al. Diabetes. 2006 Jan;55(1):128-35. Diabetes. 2006. PMID: 16380485

6

Haplotype structures and large-scale association testing of the 5' AMP-activated protein kinase genes PRKAA2, PRKAB1, and PRKAB2 [corrected] with type 2 diabetes.

Sun MW, Lee JY, de Bakker PI, Burtt NP, Almgren P, Råstam L, Tuomi T, Gaudet D, Daly MJ, Hirschhorn JN, Altshuler D, Groop L, Florez JC. Sun MW, et al. Among authors: florez jc. Diabetes. 2006 Mar;55(3):849-55. doi: 10.2337/diabetes.55.03.06.db05-1418. Diabetes. 2006. PMID: 16505254

7

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program.

Florez JC, Jablonski KA, Bayley N, Pollin TI, de Bakker PI, Shuldiner AR, Knowler WC, Nathan DM, Altshuler D; Diabetes Prevention Program Research Group. Florez JC, et al. N Engl J Med. 2006 Jul 20;355(3):241-50. doi: 10.1056/NEJMoa062418. N Engl J Med. 2006. PMID: 16855264 Free PMC article.

8

Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals.

Saxena R, Gianniny L, Burtt NP, Lyssenko V, Giuducci C, Sjögren M, Florez JC, Almgren P, Isomaa B, Orho-Melander M, Lindblad U, Daly MJ, Tuomi T, Hirschhorn JN, Ardlie KG, Groop LC, Altshuler D. Saxena R, et al. Among authors: florez jc. Diabetes. 2006 Oct;55(10):2890-5. doi: 10.2337/db06-0381. Diabetes. 2006. PMID: 17003358

9

Common variants in the ENPP1 gene are not reproducibly associated with diabetes or obesity.

Lyon HN, Florez JC, Bersaglieri T, Saxena R, Winckler W, Almgren P, Lindblad U, Tuomi T, Gaudet D, Zhu X, Cooper R, Ardlie KG, Daly MJ, Altshuler D, Groop L, Hirschhorn JN. Lyon HN, et al. Among authors: florez jc. Diabetes. 2006 Nov;55(11):3180-4. doi: 10.2337/db06-0407. Diabetes. 2006. PMID: 17065359

10

The Krüppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people.

Florez JC, Saxena R, Winckler W, Burtt NP, Almgren P, Bengtsson Boström K, Tuomi T, Gaudet D, Ardlie KG, Daly MJ, Altshuler D, Hirschhorn JN, Groop L. Florez JC, et al. Diabetes. 2006 Dec;55(12):3620-4. doi: 10.2337/db06-0867. Diabetes. 2006. PMID: 17130512

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