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Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.
Cunha DA, Igoillo-Esteve M, Gurzov EN, Germano CM, Naamane N, Marhfour I, Fukaya M, Vanderwinden JM, Gysemans C, Mathieu C, Marselli L, Marchetti P, Harding HP, Ron D, Eizirik DL, Cnop M. Cunha DA, et al. Among authors: marhfour i. Diabetes. 2012 Nov;61(11):2763-75. doi: 10.2337/db12-0123. Epub 2012 Jul 6. Diabetes. 2012. PMID: 22773666 Free PMC article.
Central role and mechanisms of β-cell dysfunction and death in friedreich ataxia-associated diabetes.
Cnop M, Igoillo-Esteve M, Rai M, Begu A, Serroukh Y, Depondt C, Musuaya AE, Marhfour I, Ladrière L, Moles Lopez X, Lefkaditis D, Moore F, Brion JP, Cooper JM, Schapira AH, Clark A, Koeppen AH, Marchetti P, Pandolfo M, Eizirik DL, Féry F. Cnop M, et al. Among authors: marhfour i. Ann Neurol. 2012 Dec;72(6):971-82. doi: 10.1002/ana.23698. Ann Neurol. 2012. PMID: 23280845 Free PMC article.
Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation.
Gurzov EN, Barthson J, Marhfour I, Ortis F, Naamane N, Igoillo-Esteve M, Gysemans C, Mathieu C, Kitajima S, Marchetti P, Ørntoft TF, Bakiri L, Wagner EF, Eizirik DL. Gurzov EN, et al. Among authors: marhfour i. Oncogene. 2012 Mar 29;31(13):1723-32. doi: 10.1038/onc.2011.353. Epub 2011 Aug 15. Oncogene. 2012. PMID: 21841823