Jochemsen AG - Search Results

1

Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer.

Lenos K, Grawenda AM, Lodder K, Kuijjer ML, Teunisse AF, Repapi E, Grochola LF, Bartel F, Hogendoorn PC, Wuerl P, Taubert H, Cleton-Jansen AM, Bond GL, Jochemsen AG. Lenos K, et al. Among authors: jochemsen ag. Cancer Res. 2012 Aug 15;72(16):4074-84. doi: 10.1158/0008-5472.CAN-12-0215. Epub 2012 Jun 14. Cancer Res. 2012. PMID: 22700878

2

Apoptin, a protein derived from chicken anemia virus, induces p53-independent apoptosis in human osteosarcoma cells.

Zhuang SM, Shvarts A, van Ormondt H, Jochemsen AG, van der Eb AJ, Noteborn MH. Zhuang SM, et al. Among authors: jochemsen ag. Cancer Res. 1995 Feb 1;55(3):486-9. Cancer Res. 1995. PMID: 7834613

3

Wilms' tumor 1-KTS isoforms induce p53-independent apoptosis that can be partially rescued by expression of the epidermal growth factor receptor or the insulin receptor.

Menke AL, Shvarts A, Riteco N, van Ham RC, van der Eb AJ, Jochemsen AG. Menke AL, et al. Among authors: jochemsen ag. Cancer Res. 1997 Apr 1;57(7):1353-63. Cancer Res. 1997. PMID: 9102224

4

Isolation and identification of the human homolog of a new p53-binding protein, Mdmx.

Shvarts A, Bazuine M, Dekker P, Ramos YF, Steegenga WT, Merckx G, van Ham RC, van der Houven van Oordt W, van der Eb AJ, Jochemsen AG. Shvarts A, et al. Among authors: jochemsen ag. Genomics. 1997 Jul 1;43(1):34-42. doi: 10.1006/geno.1997.4775. Genomics. 1997. PMID: 9226370 Free article.

5

Hdmx stabilizes Mdm2 and p53.

Stad R, Ramos YF, Little N, Grivell S, Attema J, van Der Eb AJ, Jochemsen AG. Stad R, et al. Among authors: jochemsen ag. J Biol Chem. 2000 Sep 8;275(36):28039-44. doi: 10.1074/jbc.M003496200. J Biol Chem. 2000. PMID: 10827196 Free article.

6

Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53.

Ramos YF, Stad R, Attema J, Peltenburg LT, van der Eb AJ, Jochemsen AG. Ramos YF, et al. Among authors: jochemsen ag. Cancer Res. 2001 Mar 1;61(5):1839-42. Cancer Res. 2001. PMID: 11280734

7

Hdmx and Mdm2 can repress transcription activation by p53 but not by p63.

Little NA, Jochemsen AG. Little NA, et al. Among authors: jochemsen ag. Oncogene. 2001 Jul 27;20(33):4576-80. doi: 10.1038/sj.onc.1204615. Oncogene. 2001. PMID: 11494153

8

Critical role for a central part of Mdm2 in the ubiquitylation of p53.

Meulmeester E, Frenk R, Stad R, de Graaf P, Marine JC, Vousden KH, Jochemsen AG. Meulmeester E, et al. Among authors: jochemsen ag. Mol Cell Biol. 2003 Jul;23(14):4929-38. doi: 10.1128/MCB.23.14.4929-4938.2003. Mol Cell Biol. 2003. PMID: 12832478 Free PMC article.

9

Hdmx protein stability is regulated by the ubiquitin ligase activity of Mdm2.

de Graaf P, Little NA, Ramos YF, Meulmeester E, Letteboer SJ, Jochemsen AG. de Graaf P, et al. Among authors: jochemsen ag. J Biol Chem. 2003 Oct 3;278(40):38315-24. doi: 10.1074/jbc.M213034200. Epub 2003 Jul 21. J Biol Chem. 2003. PMID: 12874296 Free article.

10

Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.

Pereg Y, Shkedy D, de Graaf P, Meulmeester E, Edelson-Averbukh M, Salek M, Biton S, Teunisse AF, Lehmann WD, Jochemsen AG, Shiloh Y. Pereg Y, et al. Among authors: jochemsen ag. Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):5056-61. doi: 10.1073/pnas.0408595102. Epub 2005 Mar 23. Proc Natl Acad Sci U S A. 2005. PMID: 15788536 Free PMC article.

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