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c-Abl phosphorylates Hdmx and regulates its interaction with p53.
Zuckerman V, Lenos K, Popowicz GM, Silberman I, Grossman T, Marine JC, Holak TA, Jochemsen AG, Haupt Y. Zuckerman V, et al. Among authors: lenos k. J Biol Chem. 2009 Feb 6;284(6):4031-9. doi: 10.1074/jbc.M809211200. Epub 2008 Dec 15. J Biol Chem. 2009. PMID: 19075013 Free article.
HDMX-L is expressed from a functional p53-responsive promoter in the first intron of the HDMX gene and participates in an autoregulatory feedback loop to control p53 activity.
Phillips A, Teunisse A, Lam S, Lodder K, Darley M, Emaduddin M, Wolf A, Richter J, de Lange J, Verlaan-de Vries M, Lenos K, Böhnke A, Bartel F, Blaydes JP, Jochemsen AG. Phillips A, et al. Among authors: lenos k. J Biol Chem. 2010 Sep 17;285(38):29111-27. doi: 10.1074/jbc.M110.129726. Epub 2010 Jul 20. J Biol Chem. 2010. PMID: 20659896 Free PMC article.
Functions of MDMX in the modulation of the p53-response.
Lenos K, Jochemsen AG. Lenos K, et al. J Biomed Biotechnol. 2011;2011:876173. doi: 10.1155/2011/876173. Epub 2011 Mar 22. J Biomed Biotechnol. 2011. PMID: 21541195 Free PMC article. Review.
Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer.
Buikhuisen JY, Gomez Barila PM, Cameron K, Suijkerbuijk SJE, Lieftink C, di Franco S, Krotenberg Garcia A, Uceda Castro R, Lenos KJ, Nijman LE, Torang A, Longobardi C, de Jong JH, Dekker D, Stassi G, Vermeulen L, Beijersbergen RL, van Rheenen J, Huveneers S, Medema JP. Buikhuisen JY, et al. Among authors: lenos kj. J Exp Clin Cancer Res. 2023 Mar 3;42(1):56. doi: 10.1186/s13046-023-02600-9. J Exp Clin Cancer Res. 2023. PMID: 36869386 Free PMC article.
Human T cell activation results in extracellular signal-regulated kinase (ERK)-calcineurin-dependent exposure of Tn antigen on the cell surface and binding of the macrophage galactose-type lectin (MGL).
van Vliet SJ, Vuist IM, Lenos K, Tefsen B, Kalay H, García-Vallejo JJ, van Kooyk Y. van Vliet SJ, et al. Among authors: lenos k. J Biol Chem. 2013 Sep 20;288(38):27519-27532. doi: 10.1074/jbc.M113.471045. Epub 2013 Aug 5. J Biol Chem. 2013. PMID: 23918927 Free PMC article.
29 results