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Identification of fifteen novel germline variants in the BRCA1 3'UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site.
Brewster BL, Rossiello F, French JD, Edwards SL, Wong M, Wronski A, Whiley P, Waddell N, Chen X, Bove B; kConFab; Hopper JL, John EM, Andrulis I, Daly M, Volorio S, Bernard L, Peissel B, Manoukian S, Barile M, Pizzamiglio S, Verderio P, Spurdle AB, Radice P, Godwin AK, Southey MC, Brown MA, Peterlongo P. Brewster BL, et al. Hum Mutat. 2012 Dec;33(12):1665-75. doi: 10.1002/humu.22159. Epub 2012 Aug 2. Hum Mutat. 2012. PMID: 22753153
Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer.
Wee EJ, Peters K, Nair SS, Hulf T, Stein S, Wagner S, Bailey P, Lee SY, Qu WJ, Brewster B, French JD, Dobrovic A, Francis GD, Clark SJ, Brown MA. Wee EJ, et al. Oncogene. 2012 Sep 20;31(38):4182-95. doi: 10.1038/onc.2011.584. Epub 2012 Jan 9. Oncogene. 2012. PMID: 22231446 Free PMC article.
Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia.
Smart CE, Clarke C, Brooks KM, Raghavendra A, Brewster BL, French JD, Hetherington R, Fleming JS, Rothnagel JA, Wainwright B, Lakhani SR, Brown MA. Smart CE, et al. Among authors: brewster bl. Breast Cancer Res Treat. 2008 Nov;112(2):237-41. doi: 10.1007/s10549-007-9859-2. Epub 2007 Dec 20. Breast Cancer Res Treat. 2008. PMID: 18095153