Chen X - Search Results

1

Identification of fifteen novel germline variants in the BRCA1 3'UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site.

Brewster BL, Rossiello F, French JD, Edwards SL, Wong M, Wronski A, Whiley P, Waddell N, Chen X, Bove B; kConFab; Hopper JL, John EM, Andrulis I, Daly M, Volorio S, Bernard L, Peissel B, Manoukian S, Barile M, Pizzamiglio S, Verderio P, Spurdle AB, Radice P, Godwin AK, Southey MC, Brown MA, Peterlongo P. Brewster BL, et al. Among authors: chen x. Hum Mutat. 2012 Dec;33(12):1665-75. doi: 10.1002/humu.22159. Epub 2012 Aug 2. Hum Mutat. 2012. PMID: 22753153

2

Intronic alterations in BRCA1 and BRCA2: effect on mRNA splicing fidelity and expression.

Chen X, Truong TT, Weaver J, Bove BA, Cattie K, Armstrong BA, Daly MB, Godwin AK. Chen X, et al. Hum Mutat. 2006 May;27(5):427-35. doi: 10.1002/humu.20319. Hum Mutat. 2006. PMID: 16619214

3

Allelic imbalance in BRCA1 and BRCA2 gene expression is associated with an increased breast cancer risk.

Chen X, Weaver J, Bove BA, Vanderveer LA, Weil SC, Miron A, Daly MB, Godwin AK. Chen X, et al. Hum Mol Genet. 2008 May 1;17(9):1336-48. doi: 10.1093/hmg/ddn022. Epub 2008 Jan 19. Hum Mol Genet. 2008. PMID: 18204050 Clinical Trial.

4

BRCA1-associated complexes: new targets to overcome breast cancer radiation resistance.

Chen X, Arciero CA, Godwin AK. Chen X, et al. Expert Rev Anticancer Ther. 2006 Feb;6(2):187-96. doi: 10.1586/14737140.6.2.187. Expert Rev Anticancer Ther. 2006. PMID: 16445371 Review.

5

BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation.

Chen X, Arciero CA, Wang C, Broccoli D, Godwin AK. Chen X, et al. Cancer Res. 2006 May 15;66(10):5039-46. doi: 10.1158/0008-5472.CAN-05-4194. Cancer Res. 2006. PMID: 16707425

6

Identifying breast cancer risk loci by global differential allele-specific expression (DASE) analysis in mammary epithelial transcriptome.

Gao C, Devarajan K, Zhou Y, Slater CM, Daly MB, Chen X. Gao C, et al. Among authors: chen x. BMC Genomics. 2012 Oct 30;13:570. doi: 10.1186/1471-2164-13-570. BMC Genomics. 2012. PMID: 23107584 Free PMC article.

7

Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.

Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R. Dong Y, et al. Among authors: chen x. Mol Cell. 2003 Nov;12(5):1087-99. doi: 10.1016/s1097-2765(03)00424-6. Mol Cell. 2003. PMID: 14636569 Free article.

8

LincIN, a novel NF90-binding long non-coding RNA, is overexpressed in advanced breast tumors and involved in metastasis.

Jiang Z, Slater CM, Zhou Y, Devarajan K, Ruth KJ, Li Y, Cai KQ, Daly M, Chen X. Jiang Z, et al. Among authors: chen x. Breast Cancer Res. 2017 May 30;19(1):62. doi: 10.1186/s13058-017-0853-2. Breast Cancer Res. 2017. PMID: 28558830 Free PMC article.

9

The Protein Encoded by the CCDC170 Breast Cancer Gene Functions to Organize the Golgi-Microtubule Network.

Jiang P, Li Y, Poleshko A, Medvedeva V, Baulina N, Zhang Y, Zhou Y, Slater CM, Pellegrin T, Wasserman J, Lindy M, Efimov A, Daly M, Katz RA, Chen X. Jiang P, et al. Among authors: chen x. EBioMedicine. 2017 Aug;22:28-43. doi: 10.1016/j.ebiom.2017.06.024. Epub 2017 Jun 27. EBioMedicine. 2017. PMID: 28687497 Free PMC article.

10

Phase II study of gefitinib in patients with relapsed or persistent ovarian or primary peritoneal carcinoma and evaluation of epidermal growth factor receptor mutations and immunohistochemical expression: a Gynecologic Oncology Group Study.

Schilder RJ, Sill MW, Chen X, Darcy KM, Decesare SL, Lewandowski G, Lee RB, Arciero CA, Wu H, Godwin AK. Schilder RJ, et al. Among authors: chen x. Clin Cancer Res. 2005 Aug 1;11(15):5539-48. doi: 10.1158/1078-0432.CCR-05-0462. Clin Cancer Res. 2005. PMID: 16061871 Clinical Trial.

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