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Targeting Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) with small molecule inhibitors for the treatment of metabolic diseases.
Cao J, Zhou Y, Peng H, Huang X, Stahler S, Suri V, Qadri A, Gareski T, Jones J, Hahm S, Perreault M, McKew J, Shi M, Xu X, Tobin JF, Gimeno RE. Cao J, et al. Among authors: gareski t. J Biol Chem. 2011 Dec 2;286(48):41838-41851. doi: 10.1074/jbc.M111.245456. Epub 2011 Oct 11. J Biol Chem. 2011. PMID: 21990351 Free PMC article.
Modulation of nutrient sensing nuclear hormone receptors promotes weight loss through appetite suppression in mice.
Perreault M, Will S, Panza D, Gareski T, Harding K, Kubasiak D, Jalenak M, Gartrell K, Wang S, Bollag G, Artis DR, Ibrahim PN, Womack P, Lin JJ, Saiah E, Mansour TS, Vlasuk GP, Erbe DV, Tobin JF. Perreault M, et al. Among authors: gareski t. Diabetes Obes Metab. 2010 Mar;12(3):234-45. doi: 10.1111/j.1463-1326.2009.01157.x. Diabetes Obes Metab. 2010. PMID: 20152000